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Actos mechanism of action

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Avatar m tn I am not physically restricted - I walk 1 mile or more day and do 10 minutes of other light exercises most days. My BP runs under 120/80 most of the time. I understand carvedilol helps prevent stiffening of the heart muscle and can help restore LV function to some degree. How specially, so it do this? What is the biochemical mechanism?
1236243 tn?1277680851 I've heard a lot of bad things about the drug Actos lately, My Doctor still has me on it, is it as bad as I'm hearing?
Avatar n tn So your taking insulin (Knowing what kind of insulin is just as important as knowing a how much) AND Actos? Usually when a person goes on Insulin they drop the actos.
489891 tn?1209058786 My question is y are you taking byetta and actos+met... and I'm on topamx, but for seizures... I'm also on actos plusmet 15/500 just once a day, with a insulin pump ( i take apidra in my pump)... byetta and actos plus met are very similar drugs doing the same thing.. the actos+met will make you gain weight very quickly. How many shots of byetta are you taking a day a long with the actos plus met? and what dose of actos are you taking and why...
Avatar n tn Is it best to take actos in the morning or evening? I am on metformin and glipized, as well. Is it best to take actos along with these medications to be more effective? This discussion is related to <a href='/posts/show/712307'>Best time to take meds</a>.
Avatar m tn The mechanism of action of CampralĀ® (acamprosate calcium) Delayed-Release Tablets in maintenance of alcohol abstinence is not completely understood. Originally, several neurotransmitter systems, including GABA, were investigated for a possible role in Campral's mechanism of action. However, recent evidence suggests Campral's main interaction is with the glutamate system. Chronic alcohol exposure is hypothesized to alter the normal balance between neuronal excitation and inhibition.
Avatar m tn http://www.nasdaq.
Avatar f tn Hi all, My hubby was dx'ed 2 weeks ago w/ diabetes II. His regular doc put him on 30 mg Actos daily. At 1st hubby's blood sugar was a whopping 390- now it's down to 76-90 in the am and no more than 180 even after lots of sugary food. Obviously the blood sugar is well under control now. The problem is, my husband's vision is going crazy! I know that diabetes can cause vision problems when blood sugar is high, but the way it's happening doesn't make sense.
Avatar m tn Oyakawa I am in my 3rd year of medical school and I was wondering the mechanism of action of steroid injections in the eyelid causing cataracts. It is not an osmotic agent so why does that occur? thanks so much.
Avatar m tn 30am wake up. 2mg Glimepride at 5:00pm before dinner. Take glucose readings just before meds in am and pm. Currently avg 167 in the am and 114 in the pm. Active during the day but little activity during the evening and night. Anyone have information about switching the 30mg Actos + 4mg Glimepride to before dinner and the 2mg Glimepride at wake up in hopes of lowering the morning readings? Thank you.
382218 tn?1341181487 Thanks for posting this DV. My favorite part was the mechanism of action for Tecfidera. "Poorly understood...
2053416 tn?1330411192 Due to a lot of weight gain. My doctor took me off actos and put me on glumetza. I also take glipizide. The gulmetza does not seem to be working for me. My sugars are in the 200 + - range. Is there another generation 1 or 2 diabetes medicine that I can take with the glipizide that will work as good as the actos did and not cost so much? I would like to get off the glumetza. I am really thinking about asking the doctor to put me back on insulin (novolin R). Thank you for your input.
Avatar f tn Plavix has a unique mechanism of action by blocking the amplification of platelet activation by released ADP, and often used with aspirin to prevent the risk of clots for the first year after DES implant. Plavix and aspirin have different mechanism of action to prevent clots. After a year, plavix is usually discontinue as the risk for clots is decreased, and aspirin is continued long term. The risk of a clot is about 3%.
Avatar n tn About the side efects, all have, but Actos can give chest pain (general ill feeling), feeling short of breath, blurred vision. Actos is an oral diabetes medicine that help control blood sugar levels.These are serious allergic signs.
178107 tn?1315947630 Actos made my appetite surge and I gained 20 lbs with combo Actos/Lantus. I went off Actos but still inject 20 units in evening. BS fast is 215. I do not EAT wrong.
Avatar n tn I have pain in the very upper back of my legs and the inside of my legs where the thigh meets the body. It began a few weeks ago. I am 64 and have been a type 2 diabetic for 5 years. I also have been treated for hypertension and high cholesterol levels since the age of 50. I take daily Glucophage 500 x 2, Januvia 100, Actos 30 (newly prescribed), Lisinopril 40, Amlodopine 10 (newly prescribed), and HCTZ 25. What do you think is the cause of my pain? Thanks.
Avatar m tn HIV is transmitted by; Unprotected penetrative anal and/or vaginal sex Sharing works with other IV drug users Mother to child You never had an exposure.
Avatar f tn I stopped actos and 75% of the symptoms are gone but I did see my doctor who ordered a CT scan which was normal. My labs have all been normal except I did show 21% atypical lymphs. Mono test was negative and so was H pylori blood test. I suspect the Actos started my problems. I felt bloated and full, pain in one specific area on left side, stomach stopped growling, etc.
Avatar f tn Potassium is a chemical element and it is part of the electrolyte that should be in balance with other lytes to adequately conduct an electrical impulse that originates with the sinus node in the right atrium. The mechanism of action is not completely understood, but what is when a voltage (unit of potential for conduction) and electrolyte there will conduction and passage of electrical impluses.
Avatar m tn http://www.medscape.com/viewarticle/578705 Ribavirin improves early responses to peginterferon through improved interferon signaling. Gastroenterology. 2010 Jul;139 The therapeutic mechanisms of ribavirin for hepatitis C are unclear. Microarray analyses have shown that ribavirin increases induction of interferon-stimulated genes. We evaluated viral kinetics, serum cytokine expression, and viral mutagenesis during early stages of peginterferon therapy with and without ribavirin.
Avatar n tn Hello, Glimiperide and Actos have good data to show that they can bring down blood sugars, with a change in A1C of between 0.5-about 1.2% each, and with both you can have a greater effect. However they depend on your body having enough of its own insulin to work. In addition, some medications work better in some people than others. Also be sure that you have made changes in your diet to help improve success in bringing your sugars down.
Avatar m tn Seeing an orthodontist is advised.
Avatar n tn Some medications are actually derived from plants. The mechanism of action and effect on the body determines the classification, therefore, laxatives can be synthetic or natural.