Due to the potential for severe interaction, concomitant use
of atorvastatin, lovastatin, or
simvastatin with telaprevir is considered contraindicated. Red yeast rice, which contains lovastatin, should also be avoided during treatment with telaprevir. Fluvastatin, pravastatin, pitavastatin, and rosuvastatin are probably safer alternatives, since they are not metabolized by CYP450 3A4.