After the fourth time, she experienced within 24 hours what seemed to be a
urinary tract infection--- dysuria, frequency, hematuria. She was prescribed Macrodantin 100 mg qid, and the symptoms began to clear up within a day; however, four days into the course, she developed rash (confluent red patches with welts) on the anterior thighs, and her doctor told her to discontinue the Macrodantin.