Levaquin and liver damage

Common Questions and Answers about Levaquin and liver damage

levaquin

The drug should be discontinued at the first appearance of a skin rash, hives, or other symptoms of an allergic reaction. Hepatotoxicity (liver damage) has been reported in patients receiving LEVAQUIN®.
I was on it for roughly 8 weeks(surgical infection) and the only side effect i had was pityriasis rosacea(sp)it's a rash from extended antibiotic use.
Good grief. I think my GP prescribed me an antibiotic that might cause liver damage. (Doxycycline) Last Thurs I developed a huge boil on my chin, it was clearly infected and grew huge in just 2 days, so I went to the GP (who knows I'm on tx), and she prescribed Doxycycline (100mg 2 times a day for 7 days). I've been taking them at a different time than my Riba, which is a good thing because I just puked my guts out.
I would attempt to answer your query regarding Levaquin. Levaquin is Levofloxacin and is once a day dosage antibiotic. The most common adverse drug reactions (≥3%) in US clinical trials were nausea, headache, diarrhea, insomnia, constipation, and dizziness. Levofloxacin is contraindicated in persons with known hypersensitivity to levofloxacin or other quinolone antibacterials.
After the levaquin I was immediately in pain, the gallbladder has been removed, there is significant damage to my liver. Levaquin FDA report is very clear, people with MS and Hep C are not to be given this drug. I trusted this doctor. All of the gains I have made are gone.
I just received some blood work back from my life insurance company (I was denied) that showed I have elevated liver enzymes and wanted to find out what these could possibly mean. I have Celiacs Sprue, was diagnosed last Nov (04), I also have pernicious anemia (B12 deficiency) which I give myself injections every month. I also have hypogammaglobulinemia, which I receive IVIG (IGG) every 4 weeks, 30 grams, I have had this for 14 years.
I have been on Penicillin for a week for a bad tooth and have had no ill effects. I have talked to the dentist, my liver doc and my GP and we all agree that the infection in the teeth can bring down my immune system and that could be the reason that I have low cbc, even while not on tx. I got a shot of Neupogen a week ago last Tues and it started me on a raging teeth-ache.
That week I saw a neurologist, dermatologist, rheumatologist and GI doctor. GI doctor told me that my liver readings were higher than last spring - I am a hep B holder and my readings were at 2000 for the HEP B virus dna and now they were at 19300 quantitatio. -my tongue started to burn at this point and it started to take away from my appetite.
Welcome back. I wondered where you went since you started this whole blog! I'm glad you've been following along. You, ggreg and April2 have really helped me through this. I know that sounds shallow but you guys can relate, and my family and friends don't take my worries seriously. I appreciate your encouragement. I made my story as short as possible, but I left out that I too have a good friend whose wife died at age 30 of breast cancer.
ALT is the most specific liver marker and my personal opinion (and that's not worth much) is that in a non cirrhotic liver low levels of ALT and AST, and I mean teens and low twenties, generally suggest that the liver is not undergoing significant injury. I know this isn't always the case but I think it is the case a lot more than not.
I was assessed with asthmatic bronchitis. I was given a nebulizer treatment and placed on Nasonex, Levaquin, keeping with Albuterol and guess what SINGULAIR was introduced by my PCP on this visit. On August 15, 2006, I underwent respiratory allergy test by Quest Diagnostic and my Immuoglobuin E (assuming Eosinophil) was out of range. In September of 2006, I had bronchitis, walking pneumonia and a viral rash that came while I was enjoying a walk in the sun at lunch.
(CT scan finally confirmed that). Then still had ear troubles and the Ketek antibiotic didn't help ENT then gave me Levaquin and more steroids(pill & injection) At same time places a vent tube in my left ear. I immediately felt a horrible pressure in my right ear but strangly enough it would sometimes feel like my left ear was full. Then I get right ear tubed. So, for almost 2 years with the tubes and able to fly.
off kilter, tight forehead, concentration issues, post nasal drip. Antibiotics are just not cutting it. I've tried zithromax, levaquin, augmentum, and now on avalox.
Viruses can cause nerve damage and widespread muscle twitching rarely, but do not tend to cause localized rashes as you describe. Fasciculations involving the whole body are more likely to be benign, especially if no other neurological signs appear over time such as muscle weakness or wasting. Fasciculations can also occur from an overacitive thyroid gland (this should be checked for with blood tests), certain medications, excercise, cold exposure, pinched nerves or spinal cord problems.
The list of 30 side effects outweighs the benefits in my opinion because I can have tendon rupture in my arms and legs at any time, hallucinations, paranoia, bowel, liver and kidney damage. I was actually debating in taking this medication because I’m scared of all that can happen but I ended up taking it. This bacteria just won’t die. If it does not get better by Monday I will have to check into the hospital. SO IF YOU BET BITTEN BY ANY ANIMAL, GET HELP!!
This new box warning via FDA is something i've been aware of for some time in patients using ciprofloxaxin, levaquin (levofloxacin), Moxifloxacin (Avelox), ofloxacin (floxin), gatifloxacin (tequin), and i'm glad it'll be highlighted on labeling, showing it's increasing incidence: risk of tendinitis and tendon rupture is further increased in those over age 60, in kidney, heart, and lung transplant recipients, and with use of concomitant steroid therapy.
As soon as I get into a place I get so dizzy and my vision is all messed up. I get so hot and sweaty and my heart races. I want my life back. I still dont believe that its just anxiety causing all of this. I feel like I have something else wrong that the doctors cant find even though i have had bloodwork, mri, ekg, and they were all normal. I started taking .25mg of xanax once a day. still dont feel any better yet. So if anybody has any help please give it to me.
Glad you are feeling better. New and improved meds are not always better for everyone. We can't assume our doctors know or remember every med we are taking and so many meds are toxic to the liver for us that have liver damage. "Patient be ware". Of course when we are ill and out of sorts that last thing we want to do is read the "Cautions" and "Possible Side Effects" on our prescription bags.
This pain would intensify which would cause me to wince in pain and then release and then repeat all over again every 5-10 seconds for about a minute. This pain did not radiate anywhere but only within a specific point. Then this same stabbing sensation occurred half way up to the first knuckle of my right middle finger about 30 minutes later. Then immediately following this finger pain I felt pain in my right foot at the joint of my middle toe.
Up to now I have had one very basic blood test carried out by my GP which I believe is generic and tests for infection, liver function and glucose levels. Just prior to my symptoms making their appearence I had a fairly stringent work related medical which involved vision tests and various nerve related tests with tuning folks scratches on the bottom of the feet etc. This all apeared normal, but of course the Doctor and I were not aware of any potential problems at this time.
Hi all. New to this. I am a 44 year old woman who is physically fit (gym 5 days a week) and eats pretty well. Approx 5 weeks ago I developed veins showing on both hands. They have not gone away and infact they are bulging most times, and I can "feel them". They have increased and I can see some starting to climb up my forearm now. Before this, my veins barely ever showed.
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But I smoked for over 20 years too, a pack to a pack and a half a day. Then they noticed nodules in my lungs and liver in 2002 or 2003 I think. Yes I am not smoking now. Was sepses in March of 2007 and they found me to have I forgot what they called it but it was like an ulcerated colitis that could have leaked into my system. I also lost the use of my legs at that time and had to keep strengthening them so as to walk again. But I still can't scooch and just stand up. It's an all out effort.
i head for some info thru a nurse friend and told me stuff like liver and kidney problem and a hint of std. but after i read all the so similar stories here, im relieved but still worries a little. there a side of this incident that teaches me to practice more on safe sex, i believe that everythings happens for a reason, and the message for me is to look after my health more, limit encounters and practice safe sex..thanks heavens.....
It is now a month later and the loose stool and diahhrea still persist. My GP insists that the Levaquin did not cause this. I went to a gastroenterologist and had a colonoscopy with biopsies taken of my rectum and colon, checking for Colitis and infection, every test came back negative, including blood work which my GP performed. All negative.
maybe more) requring 2 z packs a cipro and now levaquin. she says my immune system is very knocked; she talked about hospitalization and ventilators and such if i keep getting infections.She says there have been patients who had recurrent infections who got in this position. i thought wbc and anc were the biggies but it seems there's some other thing she means when she is talking about my immune system....what else is there?
My Alt and AFP went way up from Flagl and levaquin anti-biotic. What was your fibrosis stage before treatment? One should always be kind to their liver after SVR especially if you had any fibrosis.
I've now had rocephin, Zithromax, doxycycline, and levaquin. They all seemed to help, but that might have been a coincidence since I have had no sexual contact and barely even touched myself during these times I was on the various drugs. I still have very minor dysuria after being off all medication for a week or more. I have a prescription for flagyl in case it is trichomoniasis, but haven't been tested for it. The only tests I have had were for gonnorrea and chlamydia.
Blood tests should be performed frequently with all immunomodulators to check for effects on the bone marrow, liver, and kidneys. Blood pressure and kidney function need to be closely monitored ...." ------------------------------------------------------------------------------- No, the CCFA is not a medical journal, but at the moment I don't have time to go digging further, and this popped up in a google search for "immunomodulators".
Without examining you, I cannot say what is going on. It may be possible that there is some damage to the liver, and complete liver function tests should be analyzed by your personal physician. With a history of diabetes, you are prone to gastroparesis (i.e. delayed gastric emptying). One test that has not been mentioned is a gastric emptying scan which can diagnose this. If present, there are medications (i.e. Reglan) that can help. Followup with your personal physician is essential.
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