Estradiol receptor assay
Common Questions and Answers about Estradiol receptor assay
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Pardon my ignorance, under Estrogen
Progesterone Receptor Immunoperoxidase Assay, it states Estrogen Receptor Assay Positive 80% of cells. Same for Progesterone. Possibly is this it,staining greater than 5% of cell nuclei is considered positive. OR HER2 gene ABSENT. Average copy number is 2.3. The HER2/CEP17 ratio is 1.2 (reference range is 0.8-1.7). I do not see anything else relating to your information given.
My brother was diagnosed to have Stage III Breast Cancer..he underwent Modified Radical Mastectomy & his histopath results showed positive ER/PR/Her2Neu...what exactly does triple positive test results mean in lay man's term? ESTROGEN RECEPTOR ASSAY = POSITIVE, STAINING INTENSITY=+2, PERCENT TUMOR CELLS STAINED=+5, PROGESTERONE RECEPTOR ASSAY=POSITIVE, STAINING INTENSITY=+3, PERCENT TUMOR CELLS STAINED=+4, c-erb-B2 (Her-2/neu) =POSITIVE...
re in the reproductive age group, Tamoxifen is still your primary option for hormonal treatment. For post-menopausal women who have breast cancer, and are estrogen receptor (ER) or progesterone receptor (PR) positive, switching from Tamoxifen to Aromasin would confer an advantage in terms of reducing the risk of cancer recurrence.
The most common side effects associated with Tamoxifen are hot flashes, vaginal dryness, nausea and weight gain.
s also the HER-2 (human epidermal growth factor receptor 2) assay for determining sensitivity to Trastuzumab. Then there's the Oncotype DX which can test for sensitivity to various chemotherapy drugs. In lung cancer, there are assays for quantitative testing of epidermal growth factor receptors (EGFR), which confers sensitivity to some drugs used in lung cancer like Iressa or Tarceva. The cost of testing can range from a few hundred dollars (e.g.
Her2 NEU positive and no chemo? I don't think that is a reasonable plan. See some information below from Wikipedia. Please have a conversation with your Doctors about this. The first diagnosis and treatment for breast cancer is the most important, in my honest opinion. Please please research this before making a decision in your treatment. Please. And best wishes to you and your family. This isn't an easy road but you can do it.
Estrogen receptors and Progesterone receptors are often lumped into one category and if positive place the breast cancer into the category of hormone receptor positive breast cancer. This means that hormone therapy (the exact drug depends on the individual situation) will likely be recommended as part of the treatment plan. A Her-2 rating of 2+ suggests that the testing for this protein was done with a method called immunohistochemistry.
What are your estrogen receptor/progesterone receptor assay status as well as your Her2Neu status? What other prognostic factors are present? Your treatment protocol would also depend on the presence or absence of risk factors and also prognostic factors. These should be discussed with your oncologist.
Good luck.
many hormones play a role in gynecomastya, the main three are testosterone, estradiol and prolactine, regarding the testosterone you should have a healthy testosterone to estradiol ratio, estradiol E2 (estrogen) is a very important hormone for bothe genders and its very supportive for your immune system, your bone structure your emotions and even your sex drive but it should always be in a right balance with testosterone, if it was imbanced it will cause many troubles including gyno.
You need to consult an endocrinologist for a clinical evaluation. He would probably want a thyroid assay, CRH, and other hormones related with thermoregulation. Hope this helps. Takecare.
My baby has Atypical Cushing's and is being treated with melatonin and lignans; she has been on this treatment protocol for 2 yrs. with consistent improvement until this last test in 10/10. Her Androstenedione is really elevated bringing the progesterones up with it (and probably testosterone as well tho it wasn't included in the assay). Her cortisol is within normal range, tho it is creeping up; estradiol and aldosterone are normal.
m not waiting for the trials to be over. It took only a few months to lower my estradiol, which is at a negative 20 right now. My cancer(s) were all estrogen dependent. Oddly enough, though, not all female cancers are estrogen dependent, so have your friend check to see if hers was.
It makes me feel proactive to be on it, so I take it. Even though it makes me hurt, makes my fingers hurt, give me hot flashes...
Dude it's not performance anxiety. your testosterone numbers are really low even though they're normal. no wonder you can't perform. I take it you're a young guy, so your testosterone needs to be at least 600. Wrong estrogen test. Nonetheless, it's too high. You need to test estradiol (preferably the sensitive assay one) (too low or too high will give you erectile dysfunction), dht, and shbg.
The probable treatment plan involves hormone therapy with Femora (Letrozole) pills to suppress growth of estrogen receptor (ER) positive cancer cells, a monthly infusion of Zometa (a bisphosphonate) to delay bone complications and participation in a National Cancer Institute trial of Avastin (bevacizumab), a drug that might halt progression by blocking blood flow to the tumors.
How long after a confirmed pregnancy are you suppose to continue taking Estradiol? Just read on the internet that it can cause birth defects and I can't reach my doctor to confirm this.
GS-9620 is an orally available specific agonist of TLR-7, a highly conserved innate immune receptor. GS-9620 has demonstrated a rapid and sustained reduction in viral load and surface antigen levels in animal models of viral hepatitis (woodchuck [Stephan Menne et al, J Hepatol 2011; 54: S441] and chimpanzees [Robert E. Lanford et al, Gastroenterology 2013; 144(7):1508-1517]). In healthy volunteers and in patients with chronic hepatitis C, low doses (0.
I am on 200 mg prometrium /5 mg estradiol, and metformin as well as tirosint. The prometrium and estradiol is for hot flashes. The metformin for prediabetes, couldn't get my a1c down, and tirosint for thyroid disease. My question is this...the prometrium and estradiol are causing my blood sugars to stay high, as well as make me very tired, as well as making me gain weight. I walk briskly at least 1 hour to 1 1/2 hour daily. I watch what I eat, low sugars, etc.
Hi,
The issue with soy is that it contains chemicals that are very similar to estrogens. If the breast cancer is estrogen receptor positive, some of the treatments(Tamoxifen and others)) that are given work by blocking estrogen production. By ingesting other estrogens, there is a theoretical concern that a person could be interfering with the therapeutic effect of reducing estrogen and, in fact, give the tumor the food it needs to grow.
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