The adverse effects experienced are similar to those with use of adenosine. While adverse effects are less frequent with
dipyridamole (47% of patients), they tend to be more serious than those associated with adenosine. The most common adverse effects of dipyridamole are chest pain (19%), headache (12%), and hypotension (4.6%). In addition, 12% of patients require aminophylline for reversal of adverse effects.