Pregnancy may be complicated by new-onset or preexistent allergic disease, including rhinitis, anaphylaxis, urticaria and
atopic dermatitis. Pregnancy and
asthma is extensively studied.
Of the currently available preparations, chlorpheniramine has been recommended as the first generation antihistamine of choice for use during pregnancy. Based on the information available, loratadine or cetirizine may be considered the second generation antihistamines of choice.