Newer antidepressants don’t have the same side effect. While Paxil and Zoloft
do cause some weight gain
, other SSRIs, like Prozac, Celexa and Lexapro
, don’t. For Paxil and Zoloft, the weight gain can add up to five to 40 pounds a year. Some people do experience weight gain with Lexapro or Celexa, but most don’t. In this case, it is not a surprise to have idiosyncratic responses, since the chemical structure of all the SSRIs is so similar.