Hi
and Welcome! Yes,,
opiates do override the anti-depressants.
Opiates screw with the serotonin,,norepinephrine,,and dopamine levels in your brain. When you take opiates for a long period they will produce the dopamine for your brain instead of your brain producing it,,,your brain gets kinda lazy so to speak. From what Ive learned in aftercare,,it can take months for your brain to start reproducing these chemicals on their own.