As far as I know its been deemed safe
for pregnancy. I had to be put on a
zofran pump because I was so nauseous and vomited literally all the time. It got so bad I tore my esophagus a few times, and had to be in the hospital for fluids. That pump saved my life. I'm off it now, but still take the oral zofran as I need it. All my ultrasounds have shown that baby is perfect, and I did some hefty research before going on the pump, and couldn't find anything that said it caused defects.