I am not physically restricted - I walk 1 mile or more day and do 10 minutes of other light exercises most days. My BP runs under 120/80 most of the time. I understand carvedilol helps prevent stiffening of the heart muscle and can help restore LV function to some degree. How specially, so it do this? What is the biochemical mechanism?
The mechanism of action of Campral® (acamprosate calcium) Delayed-Release Tablets in maintenance of alcohol abstinence is not completely understood. Originally, several neurotransmitter systems, including GABA, were investigated for a possible role in Campral's mechanism of action. However, recent evidence suggests Campral's main interaction is with the glutamate system. Chronic alcohol exposure is hypothesized to alter the normal balance between neuronal excitation and inhibition.
http://www.nasdaq.
At that point, our doctor added 10 mg Zetia to his regimen because of elevated LDL particles. Also, my husband stopped all alcohol (he was a social drinker, around 2-3 glasses of wine per week) and NSAID's. A month later most of his LFT's were elevated, ALT 79, GGTP 178, ALP 113 & AST on upper end of normal at 40. The doctor said to stop the Lipitor...but stay on the Zetia...... and retest in 1-1/2 weeks which he did this past Sept. 30th.
I'm not much of a researcher, but based on my tests, jon, I disagree. After my bypass surgery, I was prescribed Simvistatatin instead of Vytorin. I think it is an insurance issue. My total cholesterol level jumped 100 points after the six week test, and remains there after the second six week test. I'm back on Vytorin. Simvastation doesn't of course work with the cholesterol produced in our own bodies.
Hips started hurting. Never had any problems with rashes, got one on my elbows and back of neck. I stopped the Zetia and it’s been 3 weeks and I’m just starting to move my hands again. When I informed my Dr. he just looked at me like “oh well”.
Getting better each day, not back to normal yet. I used to walk 5 miles a day, since all this started can’t walk like I used to. Going to try getting cholesterol down with diet.
so he looked it up on his computer and sure enough, that was one of the warnings. I stopped the Zetia and the coughing disappeared completely within a couple of weeks. The point here is that medicines, while helping one problem, frequently can cause another.
The meds I take for thyroid, reflux, heart disease and high blood pressure are synthroid, metoprolol, lisinopril, plavix, aspirin, lipitor, tricor, folic acid and nexium.
Plavix has a unique mechanism of action by blocking the amplification of platelet activation by released ADP, and often used with aspirin to prevent the risk of clots for the first year after DES implant. Plavix and aspirin have different mechanism of action to prevent clots. After a year, plavix is usually discontinue as the risk for clots is decreased, and aspirin is continued long term. The risk of a clot is about 3%.
I just got off of zetia and welchol. I could not take statins. I tried them all. Used to take Niaspan and fenofibrate but they took me off cause both cause problems in some and had not 'reduced the incidence of cardiac events'. I think they have concluded that neither do Zetia, except when used with a statin, so it is the statin doing the work. I also think Welchol has been shown to not reduce cardiac events too. not sure. I am on Repatha. Third bi weekly shot.
The Fenofibrate can cause bloating indigestion, stomach pain, and increased liver enzymes or liver problems in addition to other side effects. The Zetia can cause some of these too. Have they tested your liver enzymes yet? If so were they normal? There are other drugs for lowering cholesterol and triglycerides that work as well. You can ask him to have you try Lipitor (generic) and there is now a generic Niaspan. I know because my husband is on it.
t find the right medicine...Lipitor caused severe muscle weakness, Zetia caused all kind of digestive problems and Pravachol zapped my energy...my count actually went up 30 points while taking WelChol! My doctor is telling me that I have no other choices of medicine to lower my count (total 285, HDL 106 VLDL 21, LDL 188, Triglycerids 106.) My sister is having the same problem so I guess this problem is a family thing. I am really troubled by my doctor's lack of concern.
HIV is transmitted by;
Unprotected penetrative anal and/or vaginal sex
Sharing works with other IV drug users
Mother to child
You never had an exposure.
Vytorin is a combination, I believe, of Zocor and Zetia. Zocor should help with the cholesterol already there. If not, Lipitor has studies showing that Lipitor at 40mg can help reduce cholesterol on heart valves and in arteries. If it reduces cholesterol there, it may reduce cholesterol on the heart muscle. Cholesterol builds in the arteries, valves and muscle of the heart. In order for cholesterol to stick, there has to be a sticking spot.
Potassium is a chemical element and it is part of the electrolyte that should be in balance with other lytes to adequately conduct an electrical impulse that originates with the sinus node in the right atrium. The mechanism of action is not completely understood, but what is when a voltage (unit of potential for conduction) and electrolyte there will conduction and passage of electrical impluses.
I am 38 year old.I was diagnosed of high BP(170/105mm/hg). I was prescrbed metoprolol 50mg and amlodipine 5mg. I have been taking this medine for a year. I have been regularly checking my BP ever since. It comes to 130/75mm/hg within a month. But Still I am taking the same dosage.
My worry is : Is metoprolol and amlodipine safe to take?Since I am 38 only what would be its long term effects. That is taking the drug for over 30 years? Finally whether the dosage may be changed? Please help.
Anyone here know anything about zetia and its affect on the thyroid and or levo absorption? I have read it may affect absorption and the rx monograph says talk tp your doctor if you have thyroid disorders.
He knows I am on synthroid, but I am curious how this drug affects it.
http://www.medscape.com/viewarticle/578705
Ribavirin improves early responses to peginterferon through improved interferon signaling.
Gastroenterology. 2010 Jul;139
The therapeutic mechanisms of ribavirin for hepatitis C are unclear. Microarray analyses have shown that ribavirin increases induction of interferon-stimulated genes. We evaluated viral kinetics, serum cytokine expression, and viral mutagenesis during early stages of peginterferon therapy with and without ribavirin.
My (74 year old) father currently is taking these medications together Pravastatin Sodium 80mg, Zetia 10 mg, Isosorbide Mnonitrate 30 mg, Metoprolol tartrate 50 mg, Plavix 75 mg, Amlodipine Besylate 10 mg, Aspirin (nsaid) 81 mg low dose
The doctor told him his liver count is up 66 and the lower range is 64. Would any of these drugs or combination of these drugs make liver count increase?
Seeing an orthodontist is advised.
Actually, the Enhance trial you speak of showed that adding Zetia had no more effect on the development of plaque in the carotid arteries than those on Simvastatin alone. There was no determination made on Zetia's impact on heart disease.
It's also odd that you side effects started after years of use. Side effects from statin use almost always start within the first 90 days, but I guess everyone is different.
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