Statins work by controlling the production of cholesterol in your liver while Zetia works by preventing cholesterol to be absorbed in your digestive system.
Of the two, Crestor is the stronger of the two. In addition, recent trials have shown that adding Zetia does not improve the performance of Vytorin over Simvastatin alone.
Hello,
Statins are known to have the adverse effect of liver enzyme elevation, which is generally asymptomatic. Severe liver damage as a result of statin is virtually unknown. The current clinical practice is to discontinue statin when the liver enzymes have increased to more than three times the upper limit of normal. Although zetia on its own does not generally cause liver enzyme abnormalities, it might potentiate the enzyme abnormalities, when coadministered with a statin.
Statins work in the liver and every commercial I have seen advises not to take if you have liver problems. Zetia works in the intestines.
Was the Zetia working?
If my memory serves me correctly, MikeS is taking statins and he had a TP. He is far more knowledgeable on the subject than I am and hopefully he will see this post and give his input.
Zetia is part of a class of drugs called cholesterol absorption inhibitors.
The Fenofibrate can cause bloating indigestion, stomach pain, and increased liver enzymes or liver problems in addition to other side effects. The Zetia can cause some of these too. Have they tested your liver enzymes yet? If so were they normal? There are other drugs for lowering cholesterol and triglycerides that work as well. You can ask him to have you try Lipitor (generic) and there is now a generic Niaspan. I know because my husband is on it.
I have been having some highCholesterol level for 3 years now. I was on medication in and out as I develop side effects to the statin drugs. I was on Lipitor, then on Pravachol and lastly on Crestor. None of them had problems loweting the Choesterol levels, but muscle and joint pain even with Vit D and Co Q10 as prescribed my physician. However, I came off crestor yesterday as I started feeling Dizzy. I am normally a "healthy", active energetic person.
I am presently taking Zetia every other day. I also take Omega 3/6, vitamin A,E. With Zetia interfere with the absorption of the benefits of these supplements and if so what can I do to get the full benefit of Zetia and the supplements, if anything.
Ar there any other supplements that should be avoided while taking Zetia?
Many thanks.
The pravastatin could be the reason, however which of his liver enzymes are elevated? Let us know and I may be able to help you out.
I think it's more of which one your body will tolerate the best. Different brands seem to show different side effects in many people. Lipitor in some women have produced breast pains or enlargement and even the manufacturers cannot explain that one. Still, I suppose it's cheaper than plastic surgery. Some statins cause abdominal pains in some people, or nausea or serious muscle cramps and even damage.
After electrograms, changes in cholestrol medication,( lipitor, crestor,), now on zetia my tests keep coming in high.Outside of my lower extremities aches, which I credit to arthritis, I feel fine. Both doctors, arthritis and cardiologist, keep drawing blood with these rates still climbing. After a year of this circle, and being a believer in preventive mediciene, my concern is should I be concerne?
Thx. Mike:
Along the same lines I had read this and I remember seeing at one time about the regulators here in Can. reporting on it.
Yes... a little confusing on what exactly caused what ,however possibly because of the conflicting info. it has been put aside as an adjunct to HCV therapy.
Will
Regulators in Australia and Canada have warned since 2005 about the drug's potential to cause hepatitis, pancreatitis and depression.
I am 48 year old female, have had high cholestrol for which I have been on Zetia & Tricor for several years, now is almost normal. I had a bad reaction to the statins- ended up in the hospital with very high liver enzymes. Recently, I have been getting very lightheaded and experiencing pain in my upper arms. My doctor refered me to a cardiologist who performed the heart ultrasound and the holter which came back normal.
The recommended dose of paracetamol for a single adult is two standard 500 mg tablets. Researches have reported that the threshold for liver damage to start from a single paracetamol overdose is 15 gms (30 tablets). However liver damage could start to occur at a single overdose of 24 standard tablets or 150 mg/kg body weight, (whichever is the smaller).
I have been taking Darvocet for about two years now. I began just taking one a week at night after a bad day and it has progressed to 1-3 daily for about 6 months now. I went to the Dr. for a checkup yesterday and the ALT liver function test was high. The other liver tests were normal just that one was high. The Dr. thinks it is from my acid reflux medication and is changing that but I rarely take it. Could it be the Darvocet?
from the doc forum:
http://www.medhelp.
Can anyone tell me what it's called when you have liver damage from medications
The only way to truly ease your mind is by being totally honest with him/her. I have liver damage and kidney damage due to drugs stage 2 liver stage 3 kidney.. if your liver were damaged and you had a flare your belly would be extended/pain upper right you would be lethargic/vomiting.. other symptoms but these being severe.. It is not fun and I would not wish it on anyone.. I contracted hep C from slamming and further continued the damage through pills/alcohol..
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