Ever since I started taking Zetia and Fenofibrate together as recommended by my DR, I have put on pounds, am more bloated around the belly,a nd have persistent chest pains. I noticed this has occurred ever since I have been on cholesterol lowering meds, but is more noticeable in the past year with the new combination of drugs. I mentioned this to my DR and he said I need the drugs because of my High Cholesterol. What do you think?
Fibrates break down the particles that make triglycerides and use them in other ways in your body. Lower triglycerides can lead to increased levels of HDL ("good") cholesterol.
•Cholesterol Absorption Inhibitors (Brand name: Zetia)
A cholesterol absorption inhibitor is used to lower levels of LDL ("bad") cholesterol. This medicine can also be given in combination with a statin.
total cholesterol = 487, and triglycerides were over 2000, about 10 years ago. I have a genetic condition that causes this.
So, in spite of the risk of combining statins and fenofibrates, my GP placed me on both medicines, after consulting with his cardio doc friend.
I can't remember how long I was on these medications, but I know that I had to stop statins in general, because my body just will not tolerate them. I continued to take Tricor for quite some time.
My understanding is that the statins with the greatest LDL reducing effect are Crestor, Lipitor, Zocor, and Pravachol, in that order. I don’t mention Leschol and Mevacor since they appear to be rarely used since recently due to the aforementioned being more powerful. Do we have any available solid data on the effects of the various individual statins other than LDL reduction? For example, do we know which ones raise HDL the most? What about effects on particle size or Lp(a), etc.
My total cholesterol is 225! Says it should be less than 180! AGH! The triglycerides and HDL (good cholesterol) are good.
Umm, could this be causing my palpitations? Or what? I'm so surprised at these numbers - I am a vegetarian and am only 34. I exercise a lot and eat a lot of soy.
One thing I'm wondering is...the lady that made the appt for me told me to not eat anything after midnight the night before I had my blood taken for these tests.
Statins work in the liver and every commercial I have seen advises not to take if you have liver problems. Zetia works in the intestines.
Was the Zetia working?
If my memory serves me correctly, MikeS is taking statins and he had a TP. He is far more knowledgeable on the subject than I am and hopefully he will see this post and give his input.
Zetia is part of a class of drugs called cholesterol absorption inhibitors.
AST on upper end of normal at 40. The doctor said to stop the Lipitor...but stay on the Zetia...... and retest in 1-1/2 weeks which he did this past Sept. 30th. His ALP came down to normal at 91, his ALT stayed the same at 79, his AST stayed relatively the same at 42, but his GGTP went quite high at 240. The doctor's office called and told him to come in next week.
If it were me I would give pravastatin a chance, but if I had the same side effects and I could not live with them, I would try something like Zetia. You could also add a fenofibrate like Tricor to lower your TGLs as well, very safe and no side effects. This will help lower your overall number but will not impact your LDL which is you main issue. You really need to get that under 130 with no other risk factors.
I’m a active 68 yr. old women, that has tried 3 different statins. Everyone gave me muscle problems. Then my GP put me on Zetia. Said it would be different. After two months on it, it was worst than the statins. Woke up one morning, couldn’t close my hand. My fingers were so swollen and my both thumb joints would not bend. When I tried to bend them they clicked and was very painful.
I finally went to a specialist in Baltimore who read my history which showed all the meds I was taking and he noticed that I was taking Zetia and told me that he believed Zetia caused chronic coughing in some people; so he looked it up on his computer and sure enough, that was one of the warnings. I stopped the Zetia and the coughing disappeared completely within a couple of weeks. The point here is that medicines, while helping one problem, frequently can cause another.
I just got off of zetia and welchol. I could not take statins. I tried them all. Used to take Niaspan and fenofibrate but they took me off cause both cause problems in some and had not 'reduced the incidence of cardiac events'. I think they have concluded that neither do Zetia, except when used with a statin, so it is the statin doing the work. I also think Welchol has been shown to not reduce cardiac events too. not sure. I am on Repatha. Third bi weekly shot.
This year my triglycerides were at 535, I stopped taking a med and they went down to 212 over 3 last 3 months. My last lipid panel showed triglycerides 212, Cholesterol 191, LDL 122 and HDL 26. Results in 2020 were roughly the same numbers. I don’t really go to a General Practitioner unless it’s an emergency, do I need to see one regarding the slightly elevated triglycerides and the really low HDL? Would rather not go if not necessary. These numbers were fasting from Midnight on.
Cholesterol numbers are 110 total, 44 HDL and 58 LDL, Triglycerides are 86. As we increase will have weekly blood test for creatinine and potassium levels, also doing BP daily and recording. I have noticed as BP gets lower the heart rate increases. Is this normal with this med therapy and is this part of the remodeling? Does this look in line with current accepted treatment of major MI 6 months ago and current Ejection fraction of 25 ?
I know there is a connection with HIV and high Triglycerides and such but I am unsure of if it would be the ART or the virus itself that can cause it? Reason I ask is I have had a couple of tests, but made a couple of mistakes since then...my lipid profile showed massive elevations in triglycerides (almost 1000) I drank a lot of soda and smoked so i know those had something to do with it.
First time I have done a test and found that my triglycerides(Method-Enzymatic cholesterol esterase peroxide and found that the result is 527. How to reduce the same quickly.
hi, tr not stress yourself over thoses nmbers . yes it should be lower, they like them to be 150 and under, . he needs to execrise everyday and to eat less sugar .
my tris were over 600 two years ago , they ae now 148 which needs to be lower to. but i stoped walking and eating right. so yes its a concern but he can lower them.
I've got good LDL's and HDL's but my Try's have suddenly gone way up and NOW I know why! Thank you!
Recommended
