There are times when I pay dearly for any activity I do. Other times I can play baseball, ride a bike for hours, run with the grandkids, etc without any problems.
Usually I have physical clues beforehand that dictate the outcome. For me, a severe increase in fatigue (and I'm always fatigued) tells me to take it easy. Sometimes I forget this is my pattern, and other times I simply have to push myself to accomplish something that needs to be done.