get upset all the time, e.g. too dry, itchy, bladder
infections,
yeast infections from medication, birth control issues, and on and on and on... Women know this, even if they don't always know how to best handle it or receive news regarding it. If she's a reasonably mature woman, she'll care about her health and take the comment in stride. If you're a reasonably mature man, you'll be able to express very clearly that it's not a rejection of judgment but concern for her.