1) Vitamin B6 Deficiency
ALT enzyme requires active
vitamin B6 to function.
Vitamin B6 deficiency is uncommon, but it’s more likely to occur in the elderly, alcoholics, and people with underlying health conditions such as liver, kidney, or inflammatory diseases [4, 5].
In a 5-week study of 52 hemodialysis patients, low ALT levels were associated with vitamin B6 deficiency. ALT levels improved with daily B6 supplementation [6].
Alcoholics with low vitamin B6 levels also have low ALT levels.