The most common side effects with WELLBUTRIN XL are weight loss
of appetite, dry mouth, skin rash, sweating, ringing in the ears, shakiness, stomach pain, agitation, anxiety, dizziness, trouble sleeping, muscle pain, nausea, fast heartbeat, sore throat, and urinating more often.
Seizures may occur (studies showed an incidence of 1/1000 - 4/1000). The chances of having seizures increases with higher doses. Taking more than 450 mg/day increases the chance of serious side effects.