Viread vs hepsera
Common Questions and Answers about Viread vs hepsera
viread
ve started with Hepsera, there is no need to change. He felt that the resisitance rate for Hepsera (vs. Viread and Baraclude) is overstated; many patients develop no resistance at all, and the resistance rate, while higher than those for Viread/Baraclude, is not that much higher. Plus, if you do develop resistance, that's when you should start taking Viread (as mono or combo, he didn't say). And Viread is very effective in stopping Hepsera resistance.
i know when he starts with hepsera he feels tired at first for about few weeks and that's it..he very healthy and has no other problems. After his viral count down to zero and doctor give him viread but he has side effects, doctor said if his immune produce antibody then he can stop.
Is switching from Baraclude to Hepsera a valid treatment option, then? Shouldn't Viread have been tried next?
Should anyone be undergoing antiviral therapy with Adefovir Dipivoxil (Hepsera)? This relative of mine is originally from an Asian country. She says it's very common to be a HBV carrier in her country. She knew when she was around 35; her children have HBV also. Her son is also on Hepsera (he's on Medicaid).
I'm told he's tried different medication and his doctor settled on Adefovir. Is there any reason whatsoever for this to be the case?
My doctor suggests that I participate in the drug trial of Tenefovir (Viread) versus Tenofovir in combination with Emtricitibine (Truvada). I have chronic Hepatitis B and Lamivudine resistance last year. He gave me a document to read and I did a bit of research on internet on the side effect. My concern is the side effect especially on Kidney. Could you give me some advice if I should participate in the drug trial or stay with my current medicine Hepsera.
For someone who started her first antiviral therapy with Hepsera 1.5 years ago, do you recommend switching immediately to Viread? Those test results recently released seem to indicate swithcing is probably the best option for someone who started with Hepsera?
Would it be another monotherapy or perhaps a combo with something else? All my aunt has ever taken is Hepsera 10mg 1 every 3-5 days. As another person said, are doctors just being conservative here?
Anyone in the U.S. using Medicare Part D for Tenofovir (TDF, Viread) or Entecavir (ETV, Baraclude)?
Currently, my aunt is on Adefovir (ADV, Hepsera) and she has Medicare Part D. After asking around this forum, I now realize that she should be on the above 2 medication only! I'm in the process of getting a new doctor, but I wanna see how costly getting on those 2 drugs will be.
How much of a burden is Tenofovir or Entecavir, if you use Medicare Part D? From PharmacyChecker.
Hi,
I was diagnosed as Hep B carrier 8 years ago. My initial LFP tests are normal, and I do it every one or two years (not twice a year), and I never did any DNA QT test. Recently I did a Hep DNA QT test and it is 1060 copies/ml which is above normal range (<160 copies/ml). AFP is 7.9 above normal range (<6.1). LFP are normal. My doc prescribed Hepsera. Do I need treatment with this DNA level? Is this Hepsera the right drug for my situation?
I have chronic hepatitis B and been using Viread and Zeffix. ALT has been normal, HBV DNA has been negative and HBeAg has been positive recently. Now I am post-doctoral researcher in Paris and applied to temporary residence permit in Paris for 1-year without work permit. I have been working in an institution in my country and I can benefit from our social security system through the consulate. Namely, I do not need social security in France.
I have undergone through a pegasys injection + Hepsera Tab therapy for one year from May 2009 to April 2010. I have taken Entacavir 0.5 mg from May 2010 to October 2013. and i have been taking oral anti viral tenofo-B from November 2013 to April 2015 and in May 2015 Doctor prescribed me to start centaurus (Entecaver) in addition with Tenofo-B. My Medical history includes HBV DNA by PCR Quantitative is under 10 IU/ml after 5 Years. But HBeAg is still Reactive 27.
My Doctor first starts me on Hepsera. After 1.7 years, he switches me to Viread. I have been on Viread for 1.3 years. On couple occasions, I would forget to take my meds. I finally have purchased a watch, going off 6:00pm; 6:15pm; 6:30pm to make sure I don't miss any of my medicine.
I recently have been given promising news. I am told that my body has begun building antibodies. My current Virus DNA Ultra Qunat low and high is <100 copies/mL.
Well you can try Tenofovir and see how you tolerate it. It supposed to be slightly better then Entecavir - meaning more potent. If you have issues with TDF (Viread) then stop and try Baraclude.
They are very comparable group of drugs. With Entecavir yes it is better to take it on an empty stomach.
What I do with Baraclude is I take it at night 4 -5 hours after a meal, and then I eat 8 hours after. I find it best to keep me functional.
p.s. you don't mention about your labs btw.
when I experienced high alt, over 200 at one time, while taking truvada my dr was also very concerned if any damage to liver, then switched me back to viread, and alt was still consistently 80 to over hundred. (I was taking lamivudine, hepsera initially around 2004 and was told the hbv mutated only in a few months, then switched to viread, and the virus was quickly under control in a few months, the dr.
I was told I have hbv since birth and found out through a routine health screen in mid 90s, and been seeing same dr every 6 months since then, about 10 years ago started hepsera, and was told virus mutated, then switched to viread/truvada under clinical trial. About 2 or 3 years ago, I was told hbv surface antigens negative, about 9 month ago, hep b quant pcr result hbv dna not detected,hep b surf ag non reactive, hep b surf ab reactive, alt 47 IU/L, dr.
I start HepB treatment about 11 years ago with epivir and within a year I start developed resistance so I switched to Hepsera for about 10 years ago and swithed to viread 4 years ago to present time because it is better drug. But while I was taking Hepsera my kidney failed( I might had weak kidney but I blame hepsera for blame) and I was on dialysis last 8 years until I had kidney transplant this year July.
We are aware of how toxic viread is to kidney and taking viread was o.
Hi All,
Does any one observed efficacy differences between original and generic medicines for HepB? (for ex: between Viread/Vemilidy vs any other generic). The reason why I'm asking is due to that I have started my HepB treatment with Viread and it did magic in bringing down my HBVDNA to UND, also HBsAG quant is reduced to 4400 from 16000 and also specifically my liver histology improved a lot in ultra sound scans.
also, as far as Generic vs Brand go, are these exactly the same? and how do i make sure i am getting the same medications that they use in the united states? i have relatives that are currently in india, how can i go about telling them to see if they can get the medication from there?
On the other hand, it is generally considered safe for mothers on Viread to breakfeed - concentration of Viread in breast milk is minimal and experiences from HIV mothers on Viread indicated no significant side effects on baby. So it may be an option to delay switching until breastfeeding is over.
Just my understanding.
HR - Found your comment on taking this combo for better resistance profile very interesting and refreshing. Always gain new knowledge reading your posts. Is your suggestion base on HIV Viread/ETC resistance profile? How long can this combo goes without resistance?
1. Should I take VIREAD immediately as suggested by my primary care doctor? And why?
2. Will VIREAD change my life style, i.e. make me exercise less, no more hiking / skiing trip?
3. Am I correct that I will take VIREAD for life?
4. When will VIREAD develop resistance? Any known data / study on this?
5. What is the life expectancy can I expect?
Thank you again for sharing your information.
God Bless.
That is actually not much better than tenofovir vs tenofovir disoproxil fumarate, the actual substance in Viread. It is 50 times more potent than tenofovir.
It is all this improper simplification of callling viread tenofovir.
Tenovovir, if it would be given orally, would have no effect on HBV.
TEnofovir if given intravenously or sc would still have almost no effect on HBV in the liver. the substance has a high negative charge and cannot easlily penetrate cell membranes.
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