As far as detox- alcohol is the only detox that can kill u if I ts not medically managed and the alcohol intake was severe and/or long term abuse.tremors, seizures, agitation, anxiety, hallucinations, nausea and vomiting. Seizures and hallucinations disorientation are critical symptoms and need emergent medical help!! Opiate detox is hell. Severe agitation, anxiety, insomnia, muscle spasms, high blood pressure, sweats, puking. Diarrhea. It sucks but isn't lethal.