I am so happy to hear from others going through the same weight-gain / loss issues with Effexor. I just weaned myself off from 150 mg
to 75 mg
to nothing (I'm now using St. John's Wort as a supplement instead) in a few weeks, with lots of withdrawal symptoms/pain, etc., but I have to believe it's worth it. I, too, gained 40 pounds since starting the Effexor in February 2007.