GLD/JGO Although patients who have undergone liver transplantation are often highly motivated, treatment of this group is difficult and labor-intensive
for several reasons. Liver transplant
recipients tend to have higher viral loads, more pronounced cytopenia, and some degree of renal insufficiency. All of these factors contribute to more frequent dose reductions, greater need for use of growth factors such as erythropoietin and filgrastim (Neupogen, Amgen), and lower response rates.