Type 1 diabetes mellitus mechanism

Common Questions and Answers about Type 1 diabetes mellitus mechanism


Avatar f tn High prevalence of glucose metabolic disorders has been well documented in patients with chronic HCV infection, including insulin resistance (32%–70%), type 2 diabetes mellitus (14%–50%), and metabolic syndrome (26%–51%). In our study, type 2 diabetes mellitus was diagnosed in 79 of 280 patients (28.2%), which is a higher prevalence than that of the general population. .....
Avatar m tn The results show that several components of metabolic syndrome (diabetes mellitus, hypertension, high serum glucose, low HDL) are associated with moderate-to-severe fibrosis in these important types of chronic liver disease, especially NAFLD and HCV. However, diabetes mellitus was independently associated with moderate-to-severe fibrosis only in patients with NAFLD. Nevertheless, similar trends were seen in viral hepatitis.
Avatar m tn 6 (10.5%) had normal liver, 3.5 % (2) had Type 1 or 2 and 86% (49) had Type III or IV. One of these had cirrhosis. IR was evaluated in 102 patients. It was correlated with moderate and no alcohol intake in 81.3% and 78.7% cases respectively (p<0.05). In patients with light alcohol intake 54.8% did not presented IR. CONCLUSIONS: Light-to-moderate alcohol consumption was not associated with the severity of NAFLD in obese patients.
921323 tn?1268679412 Put the money towards the health costs of the uninsured. Or, use it to fund research in diabetes, heart disease, or any of the other countless complications of obesity. But is it too early to admit defeat? If we had done the same for cholesterol medications or diabetes medications, or even smoking patches and pills, we’d be paying for it in countless ways. So is there something unique about developing medications for obesity?
Avatar f tn I am a type 2 diabetic that SVRrd. Although I had a slow response during the first treatment, the second time I cleared relatively early, and went on to achieve sustained viral response. I think part of the misunderstanding here is that some members on this board have become obsessed by insulin resistance, and look at it as if it were a panacea to HCV treatment; but it doesn’t *preclude* SVR; it’s only another hurdle to jump on the path.
Avatar f tn These conditions are thought to be attributable to the body's immune response to HCV infection.
233616 tn?1312790796 Our data suggest that the potentially deleterious effects of metformin to AD patients may be avoided by using it in combination with insulin; the combination may result in a beneficial effect in treating both type 2 [diabetes mellitus] and in mitigating AD progression," the researchers write. AD expert Michal S.
Avatar m tn Vitamin D deficiency is linked to MS and type 1 diabetes in particular as both autoimmune diseases are more prevalent the further you live away from the equator and the UVB rays that create vitamin D. GMO's are not a listed autoimmune trigger however the hasn't been enough research. One animal study showed Bt toxins produced by GMO corn has been shown to significantly alter immune function in mice and may cause disrupted immune function in the gut.
Avatar m tn Introduction Evidence showing a higher prevalence of diabetes mellitus (DM) in patients with chronic hepatitis C virus (HCV) infection has been accumulating.[1-3] The underlying mechanisms explaining the connection between HCV and insulin resistance and the onset of type 2 DM are still unclear. Several mechanisms have been proposed, including insulin resistance and inadequate insulin secretion.[4-6] Other reports suggested that insulin resistance may just be a consequence of steatosis.
Avatar m tn In a cross-sectional survey including 9841 persons, Mehta et al found that HCV-positive persons who were older than 40 years had an increased risk for type 2 diabetes mellitus higher than 3 times compared with persons without HCV-infection Insulin resistance is the main pathogenic factor in the development of steatosis in chronic hepatitis C, both viral insulin resistance and metabolic insulin resistance could be implied in the development of steatosis.
Avatar n tn 1.mitochondria--the power plant of the cell. 2. glitazones--diabetes meds like Avandia that decrease insulin resistance but may increase triglycerides increasing cardiac risk. ---------------------------------------------------- Care & Counsel IV: Helping Patients Stay the Course on Treatment for Hepatitis C Listserve E-mail: ***@**** Web: www.projectsinknowledge.
26471 tn?1211940121 Sutapa Banerjee, Kousuke Saito, Malika Ait-Goughoulte, Keith Meyer, Ratna B Ray, Ranjit Ray Chronic hepatitis C virus (HCV) infection has a significantly increased prevalence of type 2 diabetes mellitus (T2DM). Insulin resistance is a critical component of T2DM pathogenesis. Several mechanisms are likely to be involved in the pathogenesis of HCV related insulin resistance.
1916673 tn?1420236870 35) These are a type of white blood cell and react as part of the autoimmune system defence mechanism against chronic infection, bacteria, inflammation and foreign particles. When the monocytes level is high, it confirms a dog is ill and has been for some time. Any disease that produces inflammation will trigger monocytes to increase in number. Mild to extreme stress and corticosteroid medications can also trigger an increase.
419309 tn?1326506891 "Definitely a good way to combat anxiety: with positive thinking. It’s reassuring to know that my husband and I may not be as odd as we thought we were. :: ) Thanks. " Eureka, I think you and your husband are every bit as odd as you think you are and I say that with a great deal of affection, admiration and respect. I always marvel that the two of you have found each other. I'm sure you've seen this article with all the research you do. I'm including it anyway.
Avatar n tn I know these days we do a fancy test of Hbg A1c or fructosamine , but I want you to ask for the old fasion test of glucose tolerance test!!! to me that is the only way to rule out DM!!! 2- Marked Hypertriglyceridemia 3-Amyloidosis (familial and acquired) a nonmalignant plasma cell produce monoclonal light chain immunoglobulin, which is deposited in tissues as amyloid. A minority of patients have multiple myeloma.Peripheral neuropathy is the most common initial neurologic manifestation .
Avatar f tn My cluster of autoimmune diseases is called polyglandular syndrome type 3. Vitiligo is common with thyroid disease. You don't have any white spots/patches now? I also had white spots with B12 malabsorption but those spots go away when I'm optimally treated (and comes back within 3 weeks without B12 - won't do that again!). The vitiligo stays around like a bad smell lol and it's roughly mirror image on both sides of the body. I have permanent circular patches of hair loss but not on my scalp.
Avatar f tn About half of all patients with hepatitis C and cryoglobulinemia experience symptoms. Patients with cyroglublinemia may develop type I, type II, type III or essential mixed cryoglobulinemia. Patients with type I cryoglobulinemia develop increased blood viscosity and are at risk for lymphoma, multiple myeloma, and Waldenstrom's macroglublinemia. Patients with type II and type III cryoglobulinemia are more likely to develop vasculitis, purpura, kidney disease and peripheral neuropathy.
Avatar n tn Obesity is usually defined as being 20% over ideal weight with resultant increase in certain diseases including high cholesterol levels, heart disease, high blood pressure, gallbladder disease, type II diabetes mellitus, hardening of the arteries, and degenerative arthritis. Weight loss decreases blood pressure, cholesterol levels, and improves diabetes control. PRESCRIPTION: yes GENERIC AVAILABLE: yes PREPARATIONS: Tablets: 30mg, 37.5mg.
233616 tn?1312790796 people with liver disease or liver involvement, such as diabetes mellitus, alcoholism, hemochromatosis (an iron metabolism disorder), or Thalassemia (a hereditary anemic condition); people with therapeutically-induced or naturally low gastric acid, such as those who have had gastric surgery or those using antacids on a routine basis; and persons with compromised immune systems, such as those individuals with AIDS or undergoing cancer treatment.
Avatar m tn Here's how to access the abstracts at Liver Meeting 2008. A list of all abstracts under the heading of "viral hepatitis" will follow. Not sure if late breaking abstracts are included. (1) Go to: http://www.aasld.org/Pages/Default.
Avatar f tn Older patients and patients with poorly controlled diabetes mellitus have a greater risk of developing infections during HCV treatment. (HEPATOLOGY 2010)" http://www.ncbi.nlm.nih.
181575 tn?1250202386 (Program and abstracts of the 41st Annual Meeting of the European Association for the Study of the Liver; April 26-30, 2006; Vienna, Austria.) showed that greater virologic suppression at Week 24 of telbivudine or lamivudine treatment was associated with superior clinical outcomes at Week 52. 5. "To date, we have no data demonstrating additive viral suppression from combinations of HBV drugs,...
Avatar n tn I also take the medication for type 2 diabetes. I also take glyburide for my diabetes. I would say that it is a 50/50 chance whether you would lose weight in the long run as the product wasn't designed as a weight loss product. (but I'm not a doctor so your dr. might be able to tell you what to expect).
Avatar n tn Yes, I've been mulling over similar thoughts as I try to make sense of the immunology alphabet soup. IFN is expressed in response to viral detection by immune cells. HCV has developed a couple of ways of shutting down IFN expression (<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
Avatar n tn Before I started the expectorant I was on antiobiotics of one sort or another for 1 solid year. You might try and see if this gives you some relief. I take the Mucinex extended tabs. I think it's the 600mg pills, twice a day. They're over the counter. There's no doubt that I have a chronic infection, either in my ears or sinuses. At least now I know I can live with it. It doesn't control my life anymore. If you try it keep me posted and let me know how it works for you!