truvada hbv

This is a potential concern because the drugs in Truvada – tenofovir and emtricitabine – are active against HBV as well as HIV. HIV and HBV are spread through some common transmission routes, including sexual transmission, vertical transmission (mother to child) and via multi-person use of injection equipment.

You are correct that Truvada is a combination of tenofovir and emtricitabine, and is generally prescribed for patients with HIV. Being a HBV forum, most of us know very little about Truvada except that it is prescribed off-label for HBV by some doctors, and that it is recommended for HBV patients who develop resistance to Tenofovir.

Now i saw your hbvdna inthe other post and use of truvada was correct, the viral load is too high and both hbv vaccine and hbig may fail if it is not reduced

//www.hivandhepatitis.com/hepatitis-b/hepatitis-b-topics/hbv-treatment/4073-easl-2013-truvada-works-best-for-immune-tolerant-hepatitis-b-patients-but-do-they-need-treatment these are the comments from easl where study was presented but first of all do immune tollerant patients need treatment?

So I had a discussion with my doctor yesterday regarding the recent elevation in my AST, ALT ( about 1.5 x ULN). I am LAM resistance, on Truvada for almost 2 years now. Everything else (HBV DNA undetectable, ultrasound ok, CBC, fibroscan + all other stuff i have no idea) came back normal. AST + ALT was in normal range all the time but 3 months recently have been up a bit. She advised me to continue monitoring my condition and warn me about possible resistance.

My Dr has been very involved on checks on me regularly and I feel comfortable with him. He recommended I begin to take Truvada for HBV treatment which I have been taking for 2.5 months. ( I also consulted with a Hepatologist who agreed with the treatment plan) since then I have had my liver enzyme tested regularly next week I will have a full panel again checking my viral load. My question is since I've been on Truvada my Alt and Ast have been very high.

truvada is just tenofovir+ftc, it is sueless on hbv unless non response to tenofovir, which is extremely rare it adds toxicity and higher price because truvada patent is not expiring in 2014, no difference on hbsag. instead of truvada it is best only for those non responding to combo tenofovir+lamivudine.

The main problem also is i took truvada as apart of my hiv treatment so if i decided to make hepatitis B pcr quantitative test maybe it becomes undetectable because of the seven months of truvada(i knew that truvada treat hepatitis B virus) What can I do to know if I'm infected or not? Is there any test i can do to know? Please help me I'm hopeless because of anti hbs antibody of 3.1 or 5 miu/ml I didn't remember i take any vaccine... From where did this result come from?

combo have no effect on hbv but more toxicity on you, if you have no resistance mutations baseline go for tenofovir only or tenofovir plus lamivudine which are the less toxic/more potent and retry interferon in 3 years

absolutely off label, one might even think about truvada plus immune globulins plus vaccine since truvada has been used after transplant to prevent reinfection and it worked on 100% persons it would be interesting to see a study on antivirals to prevent hbv after exposure but i guess it would be too difficult to make such a study and especially to find the subjects so transplantation might be the closest to this situation considering transplant recepients have a worst situation because they hav

I was diagnosed with chronic HBV back in Dec 2014. I was given Truvada (Prep) for treatment. I have taken it daily for 4.5 years and my viral load down has remained dormant and the HBV undetectable. Recently, I moved to a new city and my new job does not offer insurance. I cannot afford the medication without insurance as it is very expensive. Is there a chance my body could have rid itself of HBV during these 4.5 years?

Do you recommend the truvada over the viread or baraclude? If while being switched from Hepsera to truvada is there a risk that the Hep B could become active? Also , the Hepatitis B DNA is currently undetectable and the Hep B Surface AG is currently negative (both prior to transplant as well as post transplant, so far ) what are the chances that the Hep B could become active again once the Hbig infusions are stopped? Thank you.

1 - reactive) is good because low (in cronic hbv is always in the thouzands) although i am more familiar with iu/ml or s/n, when you reach 10iu/ml the possibility to have negative is very high and it is also very important to monitor if it declines from base line to 24 and 48 weeks or stays about the same i have seen a patient cleared hbv+hdv in 10 months interferon+truvada combo but truvada has more sides than etv and probably inf+entecavir is the about the same i guess interferon is the most

Currently DESCOVY 25mg TAF plus 200mg emtricitabine is alead approved for hiv in the USA and canada. It could well be used for hbv, most likely at 1/2 tablet a day for hbv for patients who do not tolerate viread. the emtricitabine. ..also called FTC, is also used in TRUVADA at the same dose, which is frequently used by hepatologists for patients with a suboptimal response to viread.

I am diagnosed with chronic Hep B and on Truvada for more than 5 years now. The disease is under control and virus is almost undetectable. I am going on business trip to a country where Hep B vaccine is a requirement for the visa. Can I take Hep B vaccine? Will it cause me any harm? Will vaccine interact with Truvada and have any side effect? Any advice will be greatly appreciated. Thnaks.

What do you think of Truvada for us? Over at UCLA Aids clinic they seem to think it will work really well for us. 3 drugs in one. Possibly add interferon along the way or in between treatments.

I'm taking Truvada now for almost 2 years (Undetectable HBV DNA, e antigen still positive, lam resistance). Can I switch to Baraclude? It will be easier for my budget since it cost way less coz' I'm planning on moving back home. I'm in the US. Any possible resistance or virus breakthrough if I decided to switch therapy?

it is very good in combo with interferon there is a case report about clearing hbv+hdv in 11months by interferon+truvada, it was hbeag postive at start of treatment my suggestion: interferon+tenofovir is already the standard for hbv+hdv and we know now that interferon clears hbv when hbsag less than 1500iu/ml and hbvdna very low or undetactable, so check your hbsag with abbott architect, the unit must be iu/ml otherwise it is not architect and it is not quantitative i'd add inf+tenofovir+a

they are dangerous because they all make resistance mutants if you have used lamivudine monotherapy, the only drug without hbv mutants is tenofovir, if viral load is 400c/ml under continuous antivirals you have resistance to them take a combo of the current antiviral+tenofovir for 2-3months and then discontinue and take tenofovir only to be very safe a combo of tenofovir+ftc (truvada)+nitazoxanide is the best and safe choice

and even so the drug is not good for hbv, in case she has also hiv the best drug is truvada which is tenofovir+ftc which is active on hiv and hbv

sorry for got to say truvada is used on hiv-hbv coinfection at the moment from many years, it is still on trial for hbv monoinfection but the combo of tdf+ftc (truvada) has been found to have very potent synergysm plus ftc is very active in lowering cccdna which correlates to hbsag.

Common Questions and Answers about Truvada hbv

truvada