Tramadol and cymbalta interaction
Common Questions and Answers about Tramadol and cymbalta interaction
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Since you are on a considerably high dose of tramadol yes, the interaction is significant and can indeed cause serotonin syndrome, Also since Cymbalta is a potent SNRI. Was the tramadol prescribed with by a doctor knowing you were using tramadol as such high dose and vice versa?
Reading that is serotonin syndrome on the internet won't improve your situation. I repeat serotonin syndrome is a medical condition that rarely cause trouble. If you experience fever then its time to go to the ER.
My doctor started me on 30 Mg of cymbalta which has progressed to 60 mg per day. I think it has helped but am experiencing some dizziness. Is it a drug interaction?
need to do own research) i stopped all med for 48 hrs and tramadol and prozac permantenly and immediatly began feeling better...i called my dr when i figured out what was wrong and her nurse said she (the doc) doesn't think i had that...i left her and every time i mention this story to docs i encounter they are blown away no-one helped me...
I was taking Tramadol 50 mg. for fibromyalgia pain for approximately seven years, always prescribed by my physician. I fluctuated between 2-4 pills per day, but usually just 2 at nighttime. Last week my doctor put me on Cymbalta and told me that I couldn't take the Tramadol with the Cymbalta, so I discontinued the it. Ever since, I'm barely getting any sleep and I seem to be breathing shallowly. Even at this dose, could I be experiencing withdrawal symptoms?
For neuropathy and other sensations I had relief with both Cymbalta and Lyrica. The only downside to the Lyrica was difficulty with cognition and drowsiness.
Savella (milnacipran) is the new medication and it works much the same as Cymbalta...it is an antidepressant.
As uk2 mentioned, the patches help with pain as well.
My current treatment is with Ultram for both FMS and RSD and Trazadone for sleep. It's much a 'trial and error'...
However, your other doctors are right too. There is no drug interaction between them, and so even if you become pregnant, there is not going to be any additional harm due to drug interaction. The safety profile of Cymbalta is not known for the unborn baby, hence it needs be taken with precaution in pregnancy. On the other hand Celebrex should be avoided during the last 3 months of pregnancy. Take care!
lower back & right leg pain NOT very consistent 2001 after 2nd pregnancy.
lower back & right leg pain VERY consistent 2006 after 3rd pregnancy.
2007 the start of wanting to chop my right leg off every night from the constant pain.
2008 dr prescribed me every pain med to try what helps. Tramadol 50mg 1/3xs a day was the winner!
later that same year got in 2 car accidents. 1st one was horrible. hit from behind on the highway, spun around, & flipped over a couple of times.
You are correct about there the MAJOR drug interaction between tramadol and sertraline (Zoloft). Please note that there are several moderate drug interactions with your medications, for example, sertraline (Zoloft), pregabalin (Lyrica), clonidine, and methocarbamol (Robaxin) all can increase side effects such dizziness, drowsiness, and impaired thinking and judgment when taken together. It would be a good idea to review your medication regimen with your provider and pharmacist.
I ran a check on the ones you listed and came up with the interaction between Cymbalta and trazodone - it says there is an increased risk of serotonin syndorme.
Some of the symptoms of serotonin syndrome are:
Cognitive effects: headache, agitation, hypomania, mental confusion, hallucinations, coma
Autonomic effects: shivering, sweating, hyperthermia, hypertension, tachycardia, nausea, diarrhea.
Somatic effects: myoclonus (muscle twitching), hyperreflexia (manifested by clonus), tremor.
I was thinking about trying st. John's wort for depression. I take tramadol for a knee alignment issue. I currently take 100mg-200mg about 3 times a week. I know there is an interaction with st. John's wort due to the seratonin increase they both cause. Am I able to take the st. John's wort on days I don't need the tramadol? If not, how long should I wait to take the St. John's wort after taking the tramadol and when would I be able to take the st.
I also ran an interaction checker on all three, Tramadol, Hydroxyzine and Synthroid, Synthroid produce no interaction with the other two, al though I di get a "Moderate" Interaction on Tramadol and Hydroxyzine as below:
MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.
No added interaction. Make sure to bring full list of all medications your husband is on to each doctor's appointment as he may see more than one prescriber and make sure to show that list to them each time they consider prescribing new medications.
Jennifer R RPH www.drugstore.
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