When my GERD was extreme, my doctor had me taking it twice a day, and suggested I take it when I heard the pots and
pans come out for breakfast and
dinner, as that is when I ate meals, other than a light snack. You have asked a question often asked, so I looked up the directives:
"Prescription omeprazole comes as a delayed-release capsule, and packets of delayed-release (long-acting) granules for suspension (to be mixed with liquid) to take by mouth.