Oh yeah, chemo has something to do with it. There is a study going on right now at UCLA about chemobrain and it's been listed on the Hopkins website as well. Your route with cancer has similarities with mine. Two port surgeries, mastectomy,chemo, radiation, mastectomy and DIEP perforator flap reconstruction. I went back to work 6/15/09 and seriously had issues remembering what I do and having to teach it at the same time. You learn coping strategies, thank goodness.