Tenofovir safety in pregnancy

Common Questions and Answers about Tenofovir safety in pregnancy

viread

Avatar f tn Tenofovir disoproxil and telbivudine are categorized as class B regarding safety in pregnancy and the other HBV drugs as class C. Lamivudine and tenofovir disoproxil have not been shown to be associated with fetal abnormalities even when used during the first trimester of pregnancy.[73] (extracted from an article in Nature by Prof. Anna Lok] 3. So, I think Lamivudine is safe. You must consult your doctors, including your Obstetrician, they must work as a team to look after you and your baby.
Avatar m tn s novel, highly potent lipid conjugate of tenofovir for treating hepatitis B virus (HBV) infection. In order to facilitate enrollment, the study is being conducted by several leading academic medical centers in Thailand, a country in which the incidence of HBV is very high. The Phase 1 portion of the study will enroll 50 healthy volunteers assigned to one of five sequential, ascending CMX157 dosing cohorts.
Avatar f tn That is actually not much better than tenofovir vs tenofovir disoproxil fumarate, the actual substance in Viread. It is 50 times more potent than tenofovir. It is all this improper simplification of callling viread tenofovir. Tenovovir, if it would be given orally, would have no effect on HBV. TEnofovir if given intravenously or sc would still have almost no effect on HBV in the liver. the substance has a high negative charge and cannot easlily penetrate cell membranes.
Avatar m tn TITLE: Safety of Tenofovir Disoproxil Fumarate (TDF) treatment for the entire pregnancy in mothers with active chronic hepatitis B or cirrhosis AUTHORS (FIRST NAME, LAST NAME): Calvin Pan1, Min Liu2, Haodong Cai2, Wei Yi2 Institutional Author(s): INSTITUTIONS (ALL): 1. Division of Gastroenterology and Hepatology, NYU Langone Medical Center, NYU School of Medicine, Flushing, NY, United States. 2. Ditan Hospital, Beijing, China.
Avatar m tn what about the Italian study that you mentioned regarding half dose of Tenofovir ? i was notice that the other nuc's used also in hiv (including the fail one), have a bigger dose in hiv then in hbv but thnofovir has the same dose and I was wandering why.
Avatar m tn Members the first line oral anti viral for hepatitis b is tenofovir and according to doctor it is long life use. My question are 1) what is the efficacy and safety of tenofovir for says 10years or 15 years or 20years ? 2) what is the longest years of taking tenofovir that we have on record now?
Avatar n tn two years before my DNA was 133 IU/MI in 2014 May ,in 2013 it was 2500iu/ml. in 2010 after my daughter birth it was 20iu/ml Alt And Ast keep rising after my daughter birth,Hbsag quantitative was 1439 iu/ml 3 years before.
Avatar m tn hbvdna undetactable in the blood doesn t mean undetactable in the liver, replication goesn on both as hbvdna, intraepatic hbvdna, cccdna yes antivirals makes impossible to develop cirrhosis and fibrosis increase is extremely rare but hepatitistechnologies products have a stronger effect regressing or blocking liver damage and probably preventing liver cancer too antivirals lower risk of liver cancer but liver cancer can happen anyway even if hbvdna is und if you can afford tenofovir+hepatiti
Avatar m tn tenofovir or truvada but it is not sure they can suppress hbvdna complitely after etv resistance the durg with more study on pregnancy is tenofovir, it is also the most potent with no resistance even in case it doesn t suppress hbvdna to und (all other dugs make resistance if hbvdna is detect for long periods)
Avatar f tn Need advise from ladies who have been on tenofovir before and throughout pregnancy. The last I wish to know is for drugs makers to recall tenofovir for pregnancy after 10years (which is quite common). My preference is of course not to take any drugs at least while trying and during 1st trimester as this is the most crucial period for fetal development. Fear is naturally health of fetus, birth defetcs and abnormality.
Avatar m tn ln=en Hepatera LLC and it`s development partner MYR GmbH today announced the initiation of MYR 202, a Phase 2b open label, randomized clinical trial to evaluate efficacy and safety of Myrcludex B in combination with tenofovir in chronically HBV/HDV сo-infected patients. 120 subjects will be enrolled in 20 centers in Russia and Germany.
Avatar m tn Bazinet and colleagues[17] conducted a randomized, controlled trial assessing the safety and efficacy of REP 2139 and a REP 2139 derivative with improved clearance (REP 2165) infused once a week in combination with tenofovir disoproxil fumarate and pegylated interferon alpha-2a in treatment-naive patients with chronic HBeAg-negative infection. This triple-combination therapy was well tolerated in all patients, and no infusion reactions were observed with either NAP.
Avatar f tn cabin,please start treatment now,your LFTS are very high,why you are putting yourself in danger,look at me i m pregnant and taking tdf,baby is growing,and one more thing,in my last pregnancy my viral load was o,and my lfts were normal always 22to 35 in my pregnancy,but after delivery my LFTS keep rising almost 3 years,but not more than 68,so your condition is very dangerous,after delivery your ALT and AST keep rising,
Avatar m tn This is a potential concern because the drugs in Truvada – tenofovir and emtricitabine – are active against HBV as well as HIV. HIV and HBV are spread through some common transmission routes, including sexual transmission, vertical transmission (mother to child) and via multi-person use of injection equipment.
Avatar m tn , since i want to have second baby soon and i dont want to take any medicine during pregnancy, especially in the first and second semester, thanks a lot in advance
Avatar n tn The following is a paper from doctors in Francel. It said you can breastfeed whilst your are on Tenofovir because "Tenofovir is not absorbed in the breast milk". However, I have googled and cannot find any reference to this claim. All the best to you and your baby. Clin Res Hepatol Gastroenterol. 2011 Jun 7. [Epub ahead of print] Hepatitis B virus infection and pregnancy. Pol S, Corouge M, Fontaine H.
Avatar m tn yes bro my doctor told me that it has much better safety profile than tenofovir and equivalent results...also he told me for long term it is safe ....
Avatar m tn There is an Australian company that is also developing a new pro-drug of Tenofovir, it will begin clinical trial in China next year. Gilead has amassed a fortune from its HIV drugs. It can afford to buy out Pharmassat(for its HCV drugs) for 11 billion dollars CASH! This company is not exactly generous or with social conscience.