sular new formulation

Tenofovir alafenamide (TAF), a new formulation that reaches higher levels in cells but allows for lower dosing, was as effective as the current tenofovir disoproxil fumarate (TDF) formulation but had less impact on markers of kidney function and bone turnover, researchers reported at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2013) this week in Denver.

I have heard a lot of people complain about the new formulation of Oxycontin .It is called OP I think .Purdue made this new formulation to stop people from abusing it but I have heard a lot of CP patients complain that it doesn't work as good as the old formulation .There is a substance that turns to a gel to keep people from snorting it or shooting it up and that may be what is causing it to not dissolve correctly .That's my best guess about it though .I would talk to my Dr about this .

How can I tell if I have the "old" or the "new" formulation of Armour thyroid?

Are you happy with the new Armour formulation? I guess they changed their formulation or something along thos lines and thats why there is a shortage. A lot of us have switched to other natural brands such as Westhroid and Naturethroid.

Hi I noticed a lot of comments on the "New" formulation of the Armour Thyroid tablets. I never got pills from my pharmacy with the "A" I swear all of mine were blank with no logo. I noticed this last batch has the "A" logo, is whiter and does not split in half well at all. Were there Armour tablets with no logo before? I am so confused and upset by this whole problem with this medication. I feel like buying a pig farm and learning how to make the stuff myself.

A while after it was reformulated, the FDA stopped production and shipments for several months, many people switched to other brands at that time and never went back. I used the new formulation for several months before it became unavailable nation wide. It is believed that the new formula which uses micro crystalline cellulose as a filler (Nature Throid changed to that as well), makes the hormone not absorb as well.

No not anymore as the new formulation did not do well for my thyroidless daughter.However, I did successfully and slowly move her over from a lifetime of Synthroid only to the original Armour (which she did great on) 1 1/2 years ago. The new Armour formula has more cellulose and less dexstrose in the fillers and binders and her freet4 dropped drastically on this and her freet3 dropped substantually. Had severe joint pain and fatigue on it within 2 weeks.

I do not see any labs listed with your post or comparisons so it is not clear if after the new formulation your numbers may have dropped a bit. How you feel is your best guide to doseage so if you don't feel well it may be in need of tweaking. Many people say the TSH is useless on combined therapy and that they feel best with the free T3 in the high normal range and the free T4 in the upper third or half.

Hi, welcome to the forum, your history is suggestive of that you may be having drug allergy to vitamin formulation. You may be hypersensitive to any component of the formulation. From your history it is suggests that you are intolerant to formulations of vitamin esp. if lactose or lactose like base is used. You need to discontinue the vitamins and go for other brands having different components. See whether you are comfortable with the new drug.

Okay so I finally finished my first inhaler of pulmicort and using a new inhaler (same dose, strength, everything). Before I wasn't getting many sideeffects just muscle pain which might be caused from not wearing my orthotics. Now over the last two days I am completely exhausted (sleeping at least 14 hours at night), muscle and joint pain and just feel fuzzy.

The founder of the company that discovered the Sovaldi hepatitis C drug, which has been listed with a cost of $1,000 for a single pill, says that it’s fairly cheap to make the basic ingredients for this well-regarded new medicine. It may cost only about $1,400 to manufacture a 12-week supply, or 84 pills, of the key ingredient in Sovaldi, excluding the costs of manufacturing plants, solvents, formulation, encapsulating and marketing.

Hi, welcome to the forum, your history is suggestive of that you may be having drug allergy to vitamin formulation. You may be hypersensitive to any component of the formulation. From your history it is suggests that you are intolerant to formulations of vitamin esp. if lactose or lactose like base is used. Abdominal bloating can also be seen due to hyperacidity, air swallowing or intolerance to other foods like gluten, certain wheat etc.

My new medication says you can break or crush the tablets in the information my consultant and pharmacy told me it would be fine to snap and swallow smaller.

If the tablets are consistently not breaking down in your GI tract, then you might want to discuss other medication options with your gastroenterologist. Salofalk is one of them, another is Colazal. There is also a new time-release, once per day formulation of mesalamine on the market called Lialda. The matrix of that formulation may be better tolerated in your GI tract. Bottom line is that you have options. I wish you well, IBD is a total drag.

Hi there Suzie, I've been taking Cilest for 5 years with no problems whatsoever. But ever since starting this new formulation of Cilest in January, I've been suffering severe daily nausea/stomach ache, vertigo, a dry cough along with lung/chest pains. My GP believes the new formulation may be the cause of my symptoms. She recommended I try to ride out the symptoms, but to seek help asap if my chest pain worsens.

Thanks All, for the comments and suggestions. I am not too worried about it, just want to make sure I'm not doing anything wrong. It sounds like I'm not, which is good! Gollie, you are correct, the Rebiject is for Rebif. I do ensure that I pull the cap off straight, so as not to bend the needle. I use the highest setting; at least I think it's the highest. The one that goes the deepest into the skin. On Rebiject the settings are 1 - 3. I use 3.

Has anyone heard of the new medicine for hep C? Or is going through the new treatment themselves?

I dont have much faith in this new formulation stopping addicts abusing their meds. All this new formulation does is prevent illicit routes of administration such as insuffulation or injection but does nothing to deter people from swallowing handfuls of said pills. This kind of arms race has done little in the past except to encourage resourceful addicts to develop their own methods to counter those of the Pharmaceutical Companies.

and abusers will just go to a herion dealer and get a cheaper fix for their sick addiction........so the new formulation equals more cash for purdue......a spike in herion use and more dead people.people that abuse oxy feel it is not like being a dirty scumbag herion addict so they use the clean all american prescription......they will still get what they nedd....they just got to be dirty herion scumbags as well......

Both of these patients had lymphopenia, a condition resulting from lower than normal lymphocytes. There is also a different formulation than will be used in the US, specifically copper will not be in the US formula. In both cases, the PML was detected early and treated successfully.

Hello, I am 61 year old male in pretty good health. I was just (2 months) diagnosed with Hashimoto's disease by my new doctor during a comprehensive physical. He is highly regarded which is why I switched from prior doc. Hypothyroidism does not run in my family history. He prescribed 25mcg Synthroid & insisted I avoid the generic. Follow up test still showed no change in TS level so he increased dose to 50 w follow up in 3 mos. Cigna's drug service sent generic levothyroxine.

Sular new formulation

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