I was diagnosed with PCOS in May. They started me
on Metformin at 500mg 2x/day, which was too harsh
on my
stomach. They dropped me down to 250mg 2x/day, which I seem to tolerate ok. I've lost about 10 lbs so far--since May, but I've given up my fast food, and soda-diet & regular. You might want to try doing something along those lines first. I was on Atkins about 4 years ago, and it's really, really tough. I lost 55lbs while on it, and then got pregnant.