If the neurotransmitters are out of balance, messages cannot get through the brain
properly. This can alter the way the brain
reacts in certain situations, leading to anxiety
Environmental factors: Trauma and stressful events, such as abuse, the death of a loved one, divorce, changing jobs or schools, may lead to GAD. GAD also may become worse during periods of stress. The use of and withdrawal from addictive substances, including alcohol, caffeine and nicotine, can also worsen anxiety.