Simvastatin vs lovastatin vs pravastatin
Common Questions and Answers about Simvastatin vs lovastatin vs pravastatin
lescol
The interaction has also been reported in patients receiving atorvastatin, lovastatin, or simvastatin with other potent CYP450 3A4 inhibitors such as azole antifungal agents, macrolide antibiotics, HIV protease inhibitors, and nefazodone. Clinically, high levels of HMG-CoA reductase inhibitory activity in plasma may be associated with an increased risk of musculoskeletal toxicity.
Lipitor (atorvastatin), Lescol (fluvastatin), Mevacor (lovastatin), Altoprev (lovastatin extended-release), Livalo (pitavastatin), Pravachol (pravastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Combination products include: Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).
The new labels will warn patients about:
Memory loss and mental confusion.
Lipitor (atorvastatin), Lescol (fluvastatin), Mevacor (lovastatin), Altoprev (lovastatin extended-release), Livalo (pitavastatin), Pravachol (pravastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Combination products include: Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).
Average incidence per 10 000 person-years for monotherapy with atorvastatin, pravastatin, or simvastatin was 0.44%"
Here's the link;
http://jama.ama-assn.org/content/292/21/2585.full
It is extremely rare and is not associated with Zocor (Sivastatin) more than any other statin. Statins are being found to be much safer than previously thought. For instance, it has been determined that statins help increase liver function in individuals with liver disease.
Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).
Lisinipril is $4/month and $10 for 90 days at WalMart and many other pharmacies that have the $4 precription plan. You pay out of pocket. Simvastatin isn't on that list, but lovastatin and pravastatin are, if your doctor feels like you could try substituting one of those. Metoprolol isn't on the $4/month plan, but atenolol is. Again, maybe your doctor would be okay with changing you from metoprolol to atenolol. It's worth talking to the doc about.
Can someone explain what, if any, evidence there for a switch from simvastatin to pravastatin? My husband's doctor said there is new evidence that simvastatin may be detrimental. Unfortunately, my husband did not quiz him further. He already has one stent in a narrow back artery but he has brought his cholesterol down considerably with the statins.
After recent cath my doctor changed my medication from vytorin ,have taken vytorin for 5 years, to lovastatin. I did ask for a cheaper medicine and lovastatin was what he came with. I have no problems or side effects . My question is lovastatin less effective then other of the same and if not why is it not used often. My engineering background comes out if I d not have proper data.
pdf
good article about the use of fluvastatin with hcv, as regards hbv simvastatin and lovastatin are the only statins i have seen studied on hbv (among the two sim at 80mg has the strongest effect)
red yeast rise (which contains naturally lovastatin, simvastatin and some other statins), simvastatin or other more powerful statins?
is simvastatin the most potent since used already with interferon and studied in vitro with antivirals (most potent sim+etv 300:1)
aslo what is the meaning of 300:1?150mg sim+0.5mg etv?
I hear this quite often. Next tie you speak to your doctor ask about Zocor. There is a generic called simvastatin and it is very cheap yet very effective.
Also, the additional med that your doctor was talking about is most likely a fenofibrate like Tricor which is commonly added to a statin med. I am on both and they have worked very well for me with no side effects.
We have been on simvastatin for (wife for 1+ years, me for 2+ years) and stopped about 5-6 months ago - wife still having pains in the butt some dizziness and leg pain, but getting better - I am having butt pain and leg pains, swollen left knee, (but joint pain seems OK on stairs), recovery seems slower than my wife's. But both of us have just been diagnosed with right enlarged renal cysts which were not there before taking simvastatin.
s production of cytochrome P450, I am wondering about switching from simvastatin to pravastatin. That would allow me to try CBD, which appears to have minimal side-effects. I also wouldn't mind getting more than a few hours of sleep per night. That said, am I taking a risk by switching statins after three decades? I haven't been able to find any significant and update research that covers this situations. Thank you.
I have been on Lipitor and simvastatin (Zocor) I have no major health problems, eat a good diet, only a few pounds too many, not enough exercise. What can I do to lower my LDL number?
It has been studied as noted by the excerpt from the NIH below. There has been a small plaque regression with LDL levels below 70, increased HDL, statin therapy and aerobic exercise;
"BACKGROUND: The purpose of this study was to explore the effect of lifestyle modification, mainly daily aerobic exercise, on coronary atherosclerosis in patients with coronary artery disease (CAD).
It seems that the main problem was with fenofibrate and pravastatin. The level was pravastatin was greatly increased. But newer info with other statins shows no danger. Atorvastatin serum levels were actually decreased.
Jack is very correct that any individual's response can vary a lot from the norm.
> Any other natural suggestions on lowering [TG]?
I've seen studies that low carb works best, but low Glycemic Index is not that far behind.
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