Simvastatin muscle weakness
Common Questions and Answers about Simvastatin muscle weakness
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Clinically, high levels of HMG-CoA reductase inhibitory activity in plasma may be associated with an increased risk of musculoskeletal toxicity. Myopathy manifested as muscle pain and/or weakness associated with grossly elevated creatine kinase exceeding ten times the upper limit of normal has been reported occasionally. Rhabdomyolysis has also occurred rarely, which may be accompanied by acute renal failure secondary to myoglobinuria and may result in death.
My endocrinologist prescribed me Atorvastatin 40mg in place of the simvastatin but it has since given my major chest pain and muscle weakness in my fingers and legs; so I was advised by the pharmacist to stop that and I have only taken the new statin twice and tonight was the second time taking it.
Is simvastatin something that can be eased up to a higher dose to do the exact same thing atorvastatin does for the bad cholesterol?
Less common are headache, dizziness, rash, sleep disturbances, muscle pain, cramps, or weakness. Both simvastatin and pravastatin have the same side effect profile, but it does depend on the individual as to whether one would cause more issues than the other."
The only negative I have read about Simvastatin in recent times is a study that showed high doses of simvastatin of 80 mg puts a patient at a greater risk for side effects including muscle damage.
All of my cholesterol-related numbers are in a healthy range, and I have never experienced any serious side effects (e.g., muscle weakness, kidney and liver impairment, etc.). I have, however, had trouble sleeping for the past several years (perhaps caused by simvastatin, perhaps not). More importantly, I have been experiencing back pain for the past few months and would like to try CBD. I am down to sleep a few hours a night.
hi just wanted to add that it sounds like part of the problem is the staten. The muscle problem and weakness. The ange and lack of interest is something else I think and maybe he is depressed? Does he have a reason to be depressed? Also, maybe check his thyroid while you are at the doctor. Tiredness and irritablility could be that. Is he sleeping too much or not enough?
Hope you can shed some light on this but I would tell the doctor all his symptoms and don't feel like they are nothing.
Fatigue and lethargy are side effects of atenolol, however, I do not see any information suggesting that muscle weakness is a side effect of atenolol. I see that you also take Vytorin. It appears that symptoms of ALS,( Lou Gehrig's Disease) have been reported to the FDA in a higher than expected number of patients taking statins. ALS is a progressive motor neuron disorder with symptoms such as difficulty walking or standing, difficulty with fine motor skills and muscle paralysis.
Research shows that 61 out of every 1000 patients on 80mg of simvastatin develop muscle problems. I do believe the half life for Simvastatin is quite short, 5 hours or less. If you take 80mg, then 5hours later only 40mg will remain. Another 5 hours only 20mg. So after 24 hours there will only be around 2-3mg in your body which is top up time.
Return to doctor for further investigation of these muscle aches.
Ramipril has been indicated to cause sexual problems, but both these drugs can affect liver function and in turn affect sexual performance.Further more, statin drugs can cause muscle weakness and may lead to a drop in overall energy level.
Whenever you suspect any side effect, you are supposed to contact your doctor, who would advise you how to correct the problem by adjusting the dosage or with alternative medicine. So, please consult your doctor for help.
t find the right medicine...Lipitor caused severe muscle weakness, Zetia caused all kind of digestive problems and Pravachol zapped my energy...my count actually went up 30 points while taking WelChol! My doctor is telling me that I have no other choices of medicine to lower my count (total 285, HDL 106 VLDL 21, LDL 188, Triglycerids 106.) My sister is having the same problem so I guess this problem is a family thing. I am really troubled by my doctor's lack of concern.
I'm hypersensitive to several cholesterol medications. They usually cause severe muscle pain and weakness.
You have a higher chance for muscle problems if you are taking certain other medicines with Lipitor. Especially telling if there are muscle problems like weakness, tenderness, or pain that happen without a good reason, and if your husband also has a fever or feel more tired than usual.
I was on Lipitor, but went on Simvastatin 20mg (much less expensive, too) and the results have been very good. Recent blood test shows LDL 45 and HDL 58, trig 55 and chol 114.
I have been taking Simvastatin on and off for years. About two years ago my doctor added ezetimibe to my regimen. It has been lowering my bad cholesterol how ever the first of this month I missed taking them for about a week and for the first time in years I felt less fatigued. I do have Fibromyalgia which is usually the cause of my fatigue, but this is a different type of fatigue. I have not restarted either of the cholesterol meds back because I have felt so much better.
I have been on 20 mg of simvastatin and 3000 mg niaspan now my ck levels have went from 60 to 295 i could hardly walk .will my levels come down if i lower dose. and reverse damage. i have 12 stents .the rest of my blood work is fine.
The short answer is that all of the above - hypothyroidism, hyperthyroidism, or other can all cause muscle weakness. Muscle weakness in the muscles you are talking about feeling weakness in, like from pushups (triceps, deltoids, maybe biceps and trapezius) are associated with hypo and hyperthyroidism though, so I think you're on the right track to look in to your thyroid hormone level as a cause, but I can't say it is definitely one of those, or which one it is.
One of my major symptoms is muscle weakness. I wish I knew more about what causes muscle weakness, as some days it isn't as bad as others. Anyhow, I don't think that most people understand that fibro & CFS patients can have this symptom. So I thought I would ask others here.... do you also have muscle weakness and if so... where ? I have it in both legs.
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