simvastatin in elderly

My elderly aunt just had to stop simvastatin due to sever back and leg pain. The pain was so bad that she was not steady on her feet, causing her to fall alot. Last monday it go so bad that I had to call her son to come pick her up and take her home with him. They read up on all of her meds called the Dr. he stopped the simvastatin and she is much better now and cont to improve. My husband is on it and has no problems. As with most drugs, they affect people different.

This is supported by large, randomized clinical trials, including the Heart Protection Study (HPS) and the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). The HPS was a large statin trial and included 20,536 participants who were followed over a 5-year period. Also, the Jupiter Study, which involved approximately 18,000 patients on Crestor 20mg, had absolutely no data to suggest that a statin has any effect on the neurologic system, including loss of memory.

Yes, just a bit more history after seeing other's more in depth questions. Also in the past, I've had along with the 2 prior nuclear sress tests, ( I DON'T believe it was Lexicon used in the past) I've also had an echocardiogram with last stress test 2 years ago which came out fine. Also bloodwork was good. I am on high blood pressure medicine, although it was jus slightly elevated, I'm also on Simvastatin although my cholesterol is only slightly elevated as well.

The class if statins that Simvastatin belongs in has a half life of only 11.3 hours at the most and it loses it's effect within 22 hours so it needs to be taken daily to get consistent results.

Stef, many thanks. Another question pls: I'm looking at beginning anti-viral. I have spoken with ROCHE guys in Nigeria and they are talking about what they call PEGASYS(If I get the the spelling, we spoke on phone) Now, what do you know about this anti-viral? Simvastatin doesn't appear available in Nigeria.

i tried it for hbsag but no effect on me and otan tried it in combo with pegintf and she had a superfast result hbsag und in less than 16weeks and then seroconverted to hbsab in the following months those on peg may try this combo to confirm if it was sim or just a coincidence

There was a study done with 550 people in 1993, that looked at the differences in treatment with simvastatin versus pravastatin. Patients were put on a cholesterol-lowering diet and given one of the medications. After 18 weeks, patients given simvastatin had significantly lower total cholesterol, lower LDL, lower triglycerides, and higher HDL cholesterol levels than those who took pravastatin.

Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).

“If you are unaware that a patient is on simvastatin and you give either boceprevir or telaprevir, the simvastatin level in the blood can go high and patients can develop muscle breakdown,” said Dr. Jensen. http://www.idse.net//ViewArticle.aspx?

I have been taking simvastatin for three weeks since having a Tia but have also had a flu like cold for ten days , I am still having aching flu like pains which I would have thought would have passed by now . I don't know if this is a side effect of the drug I'm taking 40mg a day but feel really achy will this pass .

My endocrinologist prescribed me Atorvastatin 40mg in place of the simvastatin but it has since given my major chest pain and muscle weakness in my fingers and legs; so I was advised by the pharmacist to stop that and I have only taken the new statin twice and tonight was the second time taking it. Is simvastatin something that can be eased up to a higher dose to do the exact same thing atorvastatin does for the bad cholesterol?

Zosta -10) also has the same effect as Storvas 10 mg. I have had cholecystectomy about 5 years back.

[0012] Administration of simvastatin according to the present invention has shown to both lower and maintain the tumor marker alphafetoprotein at a normal level, thereby indicating its usefulness in preventing the formation of liver cancer. The use of simvastatin in the prevention of a malignant liver tumor according to the present invention contemplates the daily administration of an effective amount of simvastatin orally.

• An increase in liver enzymes • Hepatitis, which is an inflammation of the liver that can cause tiredness or a general feeling of illness • Jaundice, or a yellowing of the skin or eyes that can occur due to liver damage • A fatty change in the liver • Cirrhosis • Hepatoma, which is a type of liver cancer. Increases in liver enzymes occur in about 1 percent of people taking simvastatin. The other liver problems mentioned occur in less than 1 percent of people.

Effective in June 2011 the FDA recommends limiting the dose of simvastatin to a maximum dose of 40 mg, with the exception of patients already taking simvastatin 80 mg daily for a period of greater than 12 months who have not developed any myalgia side effects. The FDA make this restriction because at the highest dose of simvastatin 80 mg daily the incidence of serious myopathy was higher than using other available statins.

no study for its activity on hbv, we do know it has activity but the trial has never started simvastatin lowers hcc 50% and prevents fibrosis/cirrhosis so it is indicated on all hbver, this has thousands of pateints studied for decades to find this data on hcc you better use simvastatin instead other statins, also ezetimibe has in vitro effect on hbv so these are the best choices on hbvers

Simvastatin improves final visual outcome in acute optic neuritis: a randomized study Abstract Background: In recent years, small-scale clinical trials have indicated that statins or 3-hydroxy-3-methylglutaryl coenzyme A (HMGCoA) reductase inhibitors exert pleiotropic immunomodulatory effects, with potential therapeutic implications in multiple sclerosis (MS).

The doctor is switching me to simvastatin which reacted badly with my liver in the past. Aim is to save money. Is it safe to buy Atorvastatin online ?

Hello, Lisinopril will lower your blood pressure a little more and help protect your kidneys. The Simvastatin will help keep plaque from building up in your kidneys which can cause more damage.When It comes to your health, especially serious problems, a person needs to be pro-active. If you're not comfortable with a particular physician it may be time to change. Try to get references from friends, neighbors etc. Hope you can find some answers!

potent anti hbv activity, still in vitro but if used as a combo we have nothing to lose if in vivo it doesn t work cirrhosis, reduction of portal ipertension liver cancer, reduction of HCC

As I was taking simvastatin, I was in fibrillation 17% of the time; 1 month after I stopped simvastatin, the level was down to 0%. I am now experimenting with alternative cholesterol control methods: Omega 3 gels, ground linseed, charcoal. I may also try red yeast rice extract, which got my cardiologist excited, since it is supposed to be quite effective too. Red yeast rice was, in fact, used to synthetise the first statin. This discussion is related to <a href='http://www.medhelp.

Hi Everyone. I am trying to get some answers regarding the treatment of an elderly male in the UK. He has been diagnosed with heart failure and has a leaky valve and some irregular heart rythums. At the moment he still gets breathless after walking up a few stairs and I'm not happy with this situation. He also has a persistent cough which may be linked to his medication. He does have some water retention in lower legs.

Another thought- has he been eating solid foods or is he only taking in liquids? If he has only been taking in non-solid food, this could wind up causing bulk not to form in stools.

was on lipitor for 5 months and switched two weeks ago to simvastatin in hopes of less side effects. just got some blood work done and the liver enzymes are elevated about one and a half times normal. does anyone know if its normal to see a spike in liver enzymes after switching statins or does this mean my body is rejecting the new statin?

. I am a 62 year old male. I take 40mg simvastatin for cholesterol , also 10mg amlodipine and 40 mg lisinopril for blood pressure . what are side effects? As well as this I have received letter from my Doctor stating that my medication is changing from 40 mg Simvastatin to 10 mg Atorvastatin . .BP and cholesterol is under control. Issues I have in recent years is significant and worsening swelling of ankles and legs , as well as Erectile dysfunction . Is there any better drugs or treatment?

what is the recommended dosage for simvastatin and the frequency (i mean how many times in a day) and whether this should be taken before food or after food..

Simvastatin in elderly

Common Questions and Answers about Simvastatin in elderly

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