Lamactil is a great mood stabilizer, it helps with depression immensely. I''ve been on a load of SSRI/SNRI's, and non worked for me.I'm up tp 250mgs at night ot Lamactil, and it's smoothed out my moods. It's definitely safe to up to 300, I would trust your new pdoc, I take the Lamactil at night, it makes me sleepy. Lexapro can be activating, which means it could make you hyper during the day, so your new pdoc is right.