00 pm. I have been through hell, but finally notice some differance. I was also on clonazepam 1mg. I was taking that only at nite, but had to start taking up to 3 a day. He wants me off that, but it does help with the blues,depression,head zaps, foggy head and all the other side effects I've been going through! He would like me to just take the serguel, but I can't get through very many days with just taking that.