Obviously, this should ONLY be done under the supervision of your doctor - NEVER adjust your medications
on your own.
As far as my own experience with the Lyrica
- I had always experienced increased relief whenever my doctor increased my dose - until we went from 300 mg daily to the 450. With that increase, I experienced no change in relief (or lack of at that point), and began experiencing bad side effects (weight gain, inability to concentrate, extreme sleepiness, nausea/vomiting).