I have. My brother (who has lived with me since he was 17) has been having problems daily for a month now with seizures, mostyl when he wakes up. He had been complaining of not sleeping, or not sleeping well. We went to the doctor, and they gave him a new med, but we were still seeing seizures daily. So as a last effort, I gave him 5mg of OTC melatonin, and he hasn't been showning signs of seizures for a bit. So I say, try it. Just be careful, they say it can increase seizure activity.