Other infectious pathogens, which also need to be included in the differential diagnoses, include Amebiasis, Shigellosis, Cytomegalovirus, and
Rotavirus. Inflammatory diseases of the colon which can present as UC include Crohn’s disease, ischemic colitis, radiation colitis, eosinophilic colitis, colorectal cancer, irritable bowel syndrome, and allergic reactions to medications such as mesalamine products, NSAIDs, and antibiotics.