it is now recognized that small reductions in the dose of peginterferon alfa and/or ribavirin
, particularly after patients
achieve undetectable HCV RNA, are less likely to impact SVR as long as dosing is not interrupted.[15,23]"
15. Reddy KR, Shiffman ML, Morgan TR, et al. Impact of ribavirin dose reductions in hepatitis C virus genotype 1 patients completing peginterferon alfa 2a/ribavirin treatment. Clin Gastroenterol Hepatol. 2007;5:124 129.
23. Shiffman ML, Ghany MG, Morgan TR, et al.