Raloxifene solubility

Common Questions and Answers about Raloxifene solubility

evista

Avatar f tn Lymphnodes clear and had five weeks of radiation treatment. Tried Tomxifene but made me ill. Dr, recommended Raloxifene. does Raloxifene prevent the recurrance of my type of breast cancer? Marian This discussion is related to <a href='/posts/show/261381'>Aromatase vs. Raloxifene</a>.
Avatar f tn I am supposed to start Raloxifene. This may cause hot flashes. If severe enough, dr will rx Effexor to treat flashes. I have been reading such negative information about the side effects of Effexor, and even worse, the are withdrawal symptoms if you have to get off of it. Is there anyone reading this that actually had to take effexor along with Raloxifene? If so, could you tell me please if you had a good, or bad experience? Thank you for any input.
Avatar f tn The medications currently FDA approved as chemoprevention for breast cancer are tamoxifen and raloxifene. Decisions to use a medication as chemoprevention would be made based on weighing the risks and benefits to the individual patient.
394052 tn?1203100849 less evidence was found for raloxifene. the USPSTF found good evidence that both tamoxifen and raloxifene increase the risk of thromboembolitic events (stroke, DVT, PE). they found that tamoxifen increases the risk of endometrial CA. the USPSTF recommends screening for colon CA starting at age 50 in men and women. earlier screening recommendations depend on the patient, family history and medical conditions (ie they are different for conditions such as ulcerative colitis, etc).
Avatar f tn Aside from radiation, you can ask your doctor about other breast cancer risk reduction strategies such as that of hormonal treatment with tamoxifen or raloxifene. Other breast conditions that may increase the risk of invasive cancer would include DCIS (ductal carcinoma in situ). Regards.
Avatar f tn Use of Raloxifene is intended to decrease the risk of osteoporosis and to decrease the risk of invasise breast cancer or to prevent invasive breast cancer from retuning in women who have had invasive BC. If you have questions or concerns about using it, it would be best to discuss them with the physician who prescribed it. Best wishes...
Avatar n tn I am not sure which medication your mother is taking, but Evista (raloxifene) can cause muscle cramps of the legs. Please have your mother make an appointment with her physician.
Avatar n tn I have been told by Oncologist that have 5 times risk factor for breast cancer. Am on raloxifene. Last nite I noticed some dimpling on the biopsied breast abt 1" from incision scar. Just had a manual exam by the Oncologist and don't want to seem like a hypochondriac, but should I see him again. He felt nothing during manual exam, but the lump that was removed was not palpable either and only detected by mammo.
Avatar m tn Methadone has a slow metabolism and very high fat solubility, making it longer lasting than morphine-based drugs. Methadone has a typical elimination half-life of 15 to 60 hours with an average of i would say about 22. However, metabolism rates vary greatly between individuals, up to a factor of 100 ranging from as few as 4 hours to as many as 130 hours, or even 190 hours. So it's hard to say.
Avatar m tn The water solubility of bilirubin allows the bilirubin to be excreted into bile. (Bile then is used to digest fats.) Total bilirubin, if I remember correctly, is the conjugated hemoglobin, since there is also another portion that is not conjugated. What the elevated total bilirubin means at this point is 'something' is going on, but you may need more information before your doc can determine the cause.
Avatar n tn Other forms of treatment post-operatively would include additional radiation therapy, or hormonal treatment with Tamoxifen or Raloxifene. All of these additional treatments are aimed to lessen the chance of recurrence as well as prevent the future development of frankly invasive cancers. Regards.
Avatar n tn In addition, women over the age of 35 with LCIS who are at treated at the Cancer Center have access to a similar drug, Raloxifene, that may also reduce the risk of developing breast cancer. Cancer Center physicians are participating in a clinical trial called STAR, where the effectiveness of Raloxifene is being compared to that of Tamoxifen for the prevention of breast cancer in high risk women.
Avatar f tn Osteoporosis medications like Raloxifene (Evista), alendronate (Fosomax), risendronate (Actonel) and ibandronate (Boniva) all can cause flu like symptoms in individuals that are taking them. I am not sure what medications you are on, but this could be your problem.
Avatar n tn The hormone therapy has so many side affects. The drugs suggested for me are Arimidex or Raloxifene. Is there anyone that does not take hormone therapy and is still doing well with no recurrance?
Avatar m tn The main requirements for them are (1) high IFN-inducing activity, (2) absence of side effects, (3) wide spectrum of antimicrobial activity, (4) broad therapeutic security and, (5) good solubility in water and biologic liquids. IFN inducers stimulate IFN production in different cells and organs, and that determines the strategy for their application. Amixin (OOO "Lancepharm," Moscow, Russia) induces IFN-?/? production mostly in T cells. Cycloferon (NTFF "Polysan," St.
Avatar n tn However, factors that can affect absorption include oral pH, salivary enzymes, lipid solubility, and molecular weight (molecules may be too large to pass through the mucous membranes). A sublingual product, specifically created to ensure effective absorption, is recommended.
Avatar f tn I suggest that you discuss with your oncologist regarding additional treatments like tamoxifen or raloxifene. These two drugs are proven to further decrease the chance of the cancer recurring on the same or the other breast and I believe would be of great benefit to your mother. However, these drugs have side effects that I believe are manageable and should be discussed well with the oncologist. Regards.
Avatar f tn I believe that you are a candidate for risk lowering strategies such as taking hormonal agents (raloxifene or tamoxifen), or surgery (mastectomy). All of these should be discussed with an oncologist or surgeon. Regards.
Avatar n tn Thank you for your comments... it's much appreciated! God bless you, too!
Avatar m tn There are some medications that are used to treat breast cancer that can be tried, though they would be used off label. These include tamoxifen (Soltamox) and raloxifene (Evista), here in the U.S. Another is Danazol. I don't know if they would be available in your country or not. Some of these drugs are quite potent and may have unwanted side effects. Be sure to discuss all of that with your doctor prior to taking them. The other option is the surgery.
Avatar f tn TBG excess production can be hereditary, which is X-linked dominant transmission, or it can be secondary to excess estrogens, as in pregnancy, use of oral contraceptives, hormone replacement, and medications like raloxifene or tamoxifen [4, 5]. The more highly sialylated TBG is cleared more slowly from plasma than the more positively charged TBG, because sialylation inhibits the hepatic uptake of glycoproteins.
Avatar n tn (By the way, although losartan is currently being researched in Johns Hopkins clinical trials, other ARBs such as telmisartan are probably most effective given their increased lipid solubility and thus increased tissue penetration.) I strongly encourage you to visit www.marfanlife.net and find the very lengthy thread titled "Losartan" or something to that effect. Probably some of the most important reading of your life.
Avatar m tn the brain is affected quickly as alcohol will cross what is called the blood-brain barrier due to its solubility. this can compromise involuntary actions such as heartbeat, breathing and gag reflex. organs such as the liver and pancreas can suffer tissue destruction resulting in everything from lowered function and scarring to complete organ failure. for diagnosing existing damage, your doctor can order bloodwork including a liver panel to check things like enzyme levels.
Avatar n tn Insulin glargine is a human insulin analog that has been designed to have low aqueous solubility at neutral pH. At pH 4, as in the LANTUS injection solution, it is completely soluble. After injection into the subcutaneous tissue, the acidic solution is neutralized, leading to formation of microprecipitates from which small amounts of insulin glargine are slowly released, resulting in a relatively constant concentration/time profile over 24 hours with no pronounced peak.
Avatar f tn •Treatment with the selective estrogen receptor modulator raloxifene is associated with increased bone mineral density and lower rates of vertebral, but not hip, fractures. •Use of MHT containing estrogen plus a progestogen is linked to a lower risk for colon cancer. •Raloxifene is associated with a lower risk for breast cancer. •Mammographic density is increased in women taking estrogen alone or with a progestogen.
Avatar m tn Hi & Welcome! A BB King fan, eh? Well, Congratulations on your 3 Days off Subs! While the majority of people I've known (including myself) to come off Bupe experience w/d's b/w 24 & 48 hours , some have reported that it 'ramps up'/intensifies between 72 - 96 hrs. Have you had any kind of opiate habit before? If not, it's just possible that you might experience milder w/d's than someone w/ a longer history.