Withdrawal symptoms are highest with Zoloft and
Luvox. However, due to lower protein binding in blood,
Luvox gets cleared from the body pretty fast compared to Lexapro and Zoloft, so withdrawal symptoms can abate faster.
So Zoloft and Luvox are comparable in terms of effect and use, with Zoloft having a wider clinical application. However, both are necessary to treat anxiety, depression and OCD and the benefits of their treating these disorders outweigh their side effects.