I have been on prilosec, prevacid, nexium and protonix all at one time or other for over 16 yrs on a continual basis- no problems yet- but it can cause
osteoporosis- I had a bone scan though
and am fine- I was on reglan for over 10 yrs
and it did start to give me tardive dyskinesia whih was very scary and I had to get off of it- I still get it even after stopping it at times