I'm currently taking Symlin. Has lots of pros and cons...first, I've lost about 15 pounds and have gone from 110 units of insulin (using a pump) daily to about 70 or 75.
Makes you so unbelievably nauseaus you can't eat, so losing weight isn't really a problem. Certain foods still make you so sick you pray for death even after you've adjusted to the medicine.
If you don't take it when you eat a meal...for me, it's an immediate BS of 400, no matter what I eat...