Hi there,
Both these drugs hydromorphine and
prednisolone can produce
long term effects. Morphine can cause physical dependence, decreased libido, constipation and addiction. Long term use of Prednisolone can weaken your immune system making you prone for recurrent infections. It can cause osteoporosis, stomach ulcer, cataracts, weight gain; hirsutism etc.A drug is prescribed if the potential benefits outweigh the risks. Discuss your concerns with your attending doctor.