pravastatin vs rosuvastatin

It has been studied as noted by the excerpt from the NIH below. There has been a small plaque regression with LDL levels below 70, increased HDL, statin therapy and aerobic exercise; "BACKGROUND: The purpose of this study was to explore the effect of lifestyle modification, mainly daily aerobic exercise, on coronary atherosclerosis in patients with coronary artery disease (CAD).

Crestor is a statin (rosuvastatin calcium) only, Vytorin is a statin (Simvastatin) with Zetia (ezetimibe). Statins work by controlling the production of cholesterol in your liver while Zetia works by preventing cholesterol to be absorbed in your digestive system. Of the two, Crestor is the stronger of the two. In addition, recent trials have shown that adding Zetia does not improve the performance of Vytorin over Simvastatin alone.

Lipitor (atorvastatin), Lescol (fluvastatin), Mevacor (lovastatin), Altoprev (lovastatin extended-release), Livalo (pitavastatin), Pravachol (pravastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Combination products include: Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe). The new labels will warn patients about: Memory loss and mental confusion.

After 36 weeks of treatment, the cumulative proportion of patients who reached the primary safety endpoint was lower in the pravastatin group than in the placebo group (8% vs 13%; 95% confidence interval [CI], −11.6 to 1.6; P = .1379). In fact, the mean ALT values declined from baseline in the pravastatin group, whereas the mean ALT and AST were increased from baseline in the placebo group. None of the subjects in either treatment group had an elevation of total bilirubin >2 times the ULN.

Red yeast rice, which contains lovastatin, should also be avoided during treatment with telaprevir. Fluvastatin, pravastatin, pitavastatin, and rosuvastatin are probably safer alternatives, since they are not metabolized by CYP450 3A4. All patients treated with HMG-CoA reductase inhibitors should be advised to promptly report any unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever.

Two recent trials have compared the clinical outcomes of intensive lipid lowering with atorvastatin 80 mg/day and standard lowering with pravastatin 40 mg/day. In the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT) trial, patients with acute coronary artery syndromes were enrolled, and pravastatin lowered the low-density lipoprotein (LDL)-cholesterol to 2.46 mmol/l, whereas atorvastatin lowered it to 1.60 mmol/l.

Can someone explain what, if any, evidence there for a switch from simvastatin to pravastatin? My husband's doctor said there is new evidence that simvastatin may be detrimental. Unfortunately, my husband did not quiz him further. He already has one stent in a narrow back artery but he has brought his cholesterol down considerably with the statins.

However, there is also the risk of liver inflammation due to the medicine Crestor® (rosuvastatin) and it is conceivable that there could be an additive effect of Crestor® (rosuvastatin) and INH. In addition, niacin may increase the risk of muscle disease called myopathy when used with Crestor® (rosuvastatin). Crestor® (rosuvastatin) significantly increases the INR (enhances the effect of Coumadin to make your blood “thinner” than it would be alone.

Based on a few opinions including the advice I got on this site I got started on TEVA-ROSUVASTATIN 20MG TABLET. 1 per day was the prescribed amount. I was tempted to cut the tablets in half but instead went with the doctor's recommendation. Hopefully the side effects won't be too bad. Thanks doctornee. Your advice reinforces my decision.

doctor has adviced me to take rosuvastatin and fenofibrate tablets.can you please tell me whether it helps to reduce weight?

//www.drugs.com/sfx/pravastatin-side-effects.html#consumer_Pravastatin Have you discussed this with your doctor? If you take other drugs and/or supplements check with your pharmacist regarding drug interactions.

I was on 40mg of Pravastatin and now am on 80mg. Is my doc just being aggressive? Or is there another reason for the big increase? I welcome any speculations.

I am a 39 year old, female. I was put on Pravastatin about 9 weeks ago as my cholesterol had gone from 190 to 225 from the previous year. I have a family history of heart disease (my father passed away after a second heart attack at 53). I was diagnosed with hypothyroidism 2 years ago and was placed on Levoxyl (75mg) and my levels have remained normal. I went to have my cholesterol checked after taking the pravastatin for 9 weeks.

m still trying to get a clarification. Anyway, the cardiologist put me on Amlodopine and Pravastatin. Now, on a daily basis it seems, my heart rate increases and beats at 90-115 bpm (normally in the mid 70s). At the same time, I've started on a vegetarian diet to try to lower my cholesterol. To try to make sure I get enough protein, I am using a protein drink (10-14 gr protein each). I drink 1-2 of these per day.

I was put on Pravastatin about 9 weeks ago as my cholesterol had gone from 190 to 225 from the previous year. I have a family history of heart disease (my father passed away after a second heart attack at 53). I was diagnosed with hypothyroidism 2 years ago and was placed on Levoxyl (75mg) and my levels have remained normal. I went to have my cholesterol checked after taking the pravastatin for 9 weeks.

I recently was prescripbed pravastatin and I notice a higher number when I test after a night of fasting in my Blood Glucose. Is there a posibility that could cause the rise.

Lipitor (atorvastatin), Lescol (fluvastatin), Mevacor (lovastatin), Altoprev (lovastatin extended-release), Livalo (pitavastatin), Pravachol (pravastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Combination products include: Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).

Is it safe to take Levothyroxine at the same time as Pravastatin? Also, 2 months ago, I started to take my Levothyroxine at bedtime instead of in the morning as it is more convenient. and after a recent bloodtest my GP has reduced my Thyroxine to 75mcg instead of 100mcg. Could taking it at bedtime be the reason for this reduction? I will obviously ask my GP about this on my next visit to the surgery but would be grateful for any advice.

My doctor has put me on generic pravastatin 20mg. A few days after I started the drug, I had a fever with flu-like symptom, and when that went away in a few days, I have been having hip/knee pains and fatigue that gets worse over the course of 2 weeks. My question is: Could these symptoms be related with pravastatin? Will these symptoms go away after a while?

My (74 year old) father currently is taking these medications together Pravastatin Sodium 80mg, Zetia 10 mg, Isosorbide Mnonitrate 30 mg, Metoprolol tartrate 50 mg, Plavix 75 mg, Amlodipine Besylate 10 mg, Aspirin (nsaid) 81 mg low dose The doctor told him his liver count is up 66 and the lower range is 64. Would any of these drugs or combination of these drugs make liver count increase?

Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).

I take Pravastatin, and my liver Enzymes GGT are high, but ALT and AST are in normal range, not sure why, I have heard different answers some doctors ar concern and others are not

In early September, I was prescribed a statin for the first time, 40 mg of Pravastatin, to be taken at night. After 2 weeks, I started having muscle pain/weakness in my legs but for the first time in my life had very odd heart palpatations after lying down in bed for about 10 minutes when I was first trying to sleep. I stopped taking the Pravastatin after about 1 month.

Pravastatin vs rosuvastatin

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