Pravastatin metabolism

Common Questions and Answers about Pravastatin metabolism

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Avatar n tn Two recent trials have compared the clinical outcomes of intensive lipid lowering with atorvastatin 80 mg/day and standard lowering with pravastatin 40 mg/day. In the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT) trial, patients with acute coronary artery syndromes were enrolled, and pravastatin lowered the low-density lipoprotein (LDL)-cholesterol to 2.46 mmol/l, whereas atorvastatin lowered it to 1.60 mmol/l.
Avatar f tn Can someone explain what, if any, evidence there for a switch from simvastatin to pravastatin? My husband's doctor said there is new evidence that simvastatin may be detrimental. Unfortunately, my husband did not quiz him further. He already has one stent in a narrow back artery but he has brought his cholesterol down considerably with the statins.
Avatar f tn //www.drugs.com/sfx/pravastatin-side-effects.html#consumer_Pravastatin Have you discussed this with your doctor? If you take other drugs and/or supplements check with your pharmacist regarding drug interactions.
Avatar n tn I was on 40mg of Pravastatin and now am on 80mg. Is my doc just being aggressive? Or is there another reason for the big increase? I welcome any speculations.
Avatar f tn I am a 39 year old, female. I was put on Pravastatin about 9 weeks ago as my cholesterol had gone from 190 to 225 from the previous year. I have a family history of heart disease (my father passed away after a second heart attack at 53). I was diagnosed with hypothyroidism 2 years ago and was placed on Levoxyl (75mg) and my levels have remained normal. I went to have my cholesterol checked after taking the pravastatin for 9 weeks.
Avatar m tn m still trying to get a clarification. Anyway, the cardiologist put me on Amlodopine and Pravastatin. Now, on a daily basis it seems, my heart rate increases and beats at 90-115 bpm (normally in the mid 70s). At the same time, I've started on a vegetarian diet to try to lower my cholesterol. To try to make sure I get enough protein, I am using a protein drink (10-14 gr protein each). I drink 1-2 of these per day.
Avatar f tn I was put on Pravastatin about 9 weeks ago as my cholesterol had gone from 190 to 225 from the previous year. I have a family history of heart disease (my father passed away after a second heart attack at 53). I was diagnosed with hypothyroidism 2 years ago and was placed on Levoxyl (75mg) and my levels have remained normal. I went to have my cholesterol checked after taking the pravastatin for 9 weeks.
Avatar n tn I recently was prescripbed pravastatin and I notice a higher number when I test after a night of fasting in my Blood Glucose. Is there a posibility that could cause the rise.
Avatar m tn Is it safe to take Levothyroxine at the same time as Pravastatin? Also, 2 months ago, I started to take my Levothyroxine at bedtime instead of in the morning as it is more convenient. and after a recent bloodtest my GP has reduced my Thyroxine to 75mcg instead of 100mcg. Could taking it at bedtime be the reason for this reduction? I will obviously ask my GP about this on my next visit to the surgery but would be grateful for any advice.
1806721 tn?1554333407 My doctor has put me on generic pravastatin 20mg. A few days after I started the drug, I had a fever with flu-like symptom, and when that went away in a few days, I have been having hip/knee pains and fatigue that gets worse over the course of 2 weeks. My question is: Could these symptoms be related with pravastatin? Will these symptoms go away after a while?
Avatar n tn My (74 year old) father currently is taking these medications together Pravastatin Sodium 80mg, Zetia 10 mg, Isosorbide Mnonitrate 30 mg, Metoprolol tartrate 50 mg, Plavix 75 mg, Amlodipine Besylate 10 mg, Aspirin (nsaid) 81 mg low dose The doctor told him his liver count is up 66 and the lower range is 64. Would any of these drugs or combination of these drugs make liver count increase?
179856 tn?1333547362 Pfeffer et al, in the prospective pravastatin pooling project, observed that 0.5% of the patients who received 40 mg of pravastatin had ALT levels >5 times ULN and 0.2% had ALT levels >9 times ULN (Circulation 2002;105:2341–2346). Interestingly, during several statin trials, investigators observed similar incidence of increased liver enzymes in patients receiving placebo.
Avatar m tn I take Pravastatin, and my liver Enzymes GGT are high, but ALT and AST are in normal range, not sure why, I have heard different answers some doctors ar concern and others are not
Avatar n tn In early September, I was prescribed a statin for the first time, 40 mg of Pravastatin, to be taken at night. After 2 weeks, I started having muscle pain/weakness in my legs but for the first time in my life had very odd heart palpatations after lying down in bed for about 10 minutes when I was first trying to sleep. I stopped taking the Pravastatin after about 1 month.
Avatar m tn [12, 76–78] In a large randomised, prospective, placebo-controlled trial with high-dose pravastatin (which, in particular, does not undergo P450 metabolism) in hypercholesterolaemic patients with compensated liver disease due to mostly non-alcoholic steatohepatitis or HCV, the cumulative risk of doubling an elevated baseline ALT value over 36 weeks was in fact lower in the pravastatin-treated group compared with untreated controls (7.5% vs. 12.5%).
Avatar m tn 59 yo white male. 1 year post MI with two stents in my RCA. I am active and with high a normal BMI of 25 No problem walking a fast mile or with light exercise. My LVEF was 50% right after MI and 45% 2 months later. due for another echo in 2 months. my lipids are under control - LDL < 70 and TC < 140, with or without the 10 mg pravastatin I am prescribed as I eat mostly a quality plant based diet, low in fats and simple carbs.. My question has to do with drugs.
1688079 tn?1305854113 The Hospitalist put me on metoprolol 25mg every 12hrs and pravastatin 10mg once a day. Put me on a cardio diet.  What does all this mean and why am I on a beta blocker??
Avatar m tn Does anyone know if having your Gallbladder removed slows down your metabolism? or does it speed it up? What have you experienced?
Avatar f tn If you really want to kick-start your metabolism, you may also try dividing your meals up into smaller portions that you eat more often throughout the day. Every time you eat, it helps your metabolism rise, so as strange as it may sound, eating frequently can help you lose weight or maintain a healthy weight. Take care!
1203175 tn?1265553335 Anyone know how to kick start your metabolism so you start losing pounds, other than weight loss medications? Will not use those.
1397290 tn?1357777871 Calorie-intake should be according to your physical activity. 2800-3000 is quite a lot, which if you don't gain of it, you should perhaps seek professional aid.
Avatar f tn s why I was in the hospital a couple of months ago. They started me on Plavix and Pravastatin while I was there. After 2 doses of both of these meds I started having bladder pain and urgency. I've had this off and on again problem for 2 months now. I did find out about a month ago that the Pravastatin can cause urinary problems, but I just found out a few days ago that the Plavix can too. My Cardiologist wants to keep me on the Plavix for a year.