Pravastatin and muscle pain
Common Questions and Answers about Pravastatin and muscle pain
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The study found that the patients on simvastatin achieved the target LDL level of less than 130, more than those on pravastatin (65 percent on simvastatin versus 35 percent on pravastatin). The most common side effects of the statins in general are nausea, gas, and upset stomach. Less common are headache, dizziness, rash, sleep disturbances, muscle pain, cramps, or weakness.
I have been having a constant chest pounding and pain radiating all over my left and right breast area, all tests done proved negative for heart condition but the pain rather than decreasing, seem to be increasing in intensity. I am on LISINOPRIL-HCTZ 20-25MG and BYSTOLIC for HBP I am also on PRAVASTATIN for Cholesterol. I recently had to stop the Bystolic because my heart rate was low between 45-62.
Dr had changed from Lipitor (generic) to Pravastatin 40 mg, but still horrible muscle pain. Dr wants to put on another statin( saying this has less side effects) and extremly expensive...But I would like to try a Non Statin is there is one on the market, or would there be supplements that are available and have good results?
Mainly I would like names of non statins to research and discuss.
After 2 weeks, I started having muscle pain/weakness in my legs but for the first time in my life had very odd heart palpatations after lying down in bed for about 10 minutes when I was first trying to sleep. I stopped taking the Pravastatin after about 1 month. I've been off of it now for about 3 weeks and am still having the palpitations but only after lying down in bed when I try to go to sleep. I've never experienced anyt type of heart palpitations befroe.
) For the past 20 years, I have avoided NSAIDs, acetaminophens, other pain relievers and muscle relaxants because of their adverse effects to liver and kidneys (personally more significant because my dad had kidney disease). Since cannabidiol inhibits the liver's production of cytochrome P450, I am wondering about switching from simvastatin to pravastatin. That would allow me to try CBD, which appears to have minimal side-effects.
//www.drugs.com/sfx/pravastatin-side-effects.html#consumer_Pravastatin
Have you discussed this with your doctor? If you take other drugs and/or supplements check with your pharmacist regarding drug interactions.
Clinically, high levels of HMG-CoA reductase inhibitory activity in plasma may be associated with an increased risk of musculoskeletal toxicity. Myopathy manifested as muscle pain and/or weakness associated with grossly elevated creatine kinase exceeding ten times the upper limit of normal has been reported occasionally. Rhabdomyolysis has also occurred rarely, which may be accompanied by acute renal failure secondary to myoglobinuria and may result in death.
Chronic headache, neck and shoulder pain, ear aches, very weak and fatiqued. a dry course cough, no phlem, no fever even though I feel aching and stiffness all over,sometimes even my skin hurts. all my labs came back normal except for elevated cholesterol, c-reactive protein sl elevated, and liver panel barely elevated. I was started and pravastatin 4 weeks ago and my symptoms seem worse.
It can produce intense pain and muscle cramps can develop in any muscle in the body although they most often occur in the calf or foot.
Muscle cramps usually happen while lying in bed or playing sports or exercising. Overuse, injury, muscle strain, or staying in the same position for a long time can produce cramping.
Without knowing the cause one cannot evaluate any risk associated with farther bike riding activity.
I explained over the last 4 months, my fatigue and pain in muscles and joints is worsening, and unbearable. He stated new tests show that statins, especially prevastatin is causing some, and in my case irreversible muscle damage and waste. These side effects we are experiencing are also those of MS patients with lesion 2 expansion in spinal cord vertabrae. I will keep you posted on next Tuesday blood test. But he is good doctor, I trust him, and I see his concern on his face....stop taking it!
Two recent trials have compared the clinical outcomes of intensive lipid lowering with atorvastatin 80 mg/day and standard lowering with pravastatin 40 mg/day. In the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT) trial, patients with acute coronary artery syndromes were enrolled, and pravastatin lowered the low-density lipoprotein (LDL)-cholesterol to 2.46 mmol/l, whereas atorvastatin lowered it to 1.60 mmol/l.
I recently was prescripbed pravastatin and I notice a higher number when I test after a night of fasting in my Blood Glucose. Is there a posibility that could cause the rise.
59 yo white male. 1 year post MI with two stents in my RCA. I am active and with high a normal BMI of 25 No problem walking a fast mile or with light exercise. My LVEF was 50% right after MI and 45% 2 months later. due for another echo in 2 months. my lipids are under control - LDL < 70 and TC < 140, with or without the 10 mg pravastatin I am prescribed as I eat mostly a quality plant based diet, low in fats and simple carbs..
My question has to do with drugs.
t seem overly concerned. He said I could go off the pravastatin and see how my numbers were with diet and exercise alone. I have been on a good routine with proper diet and regular exercise and I am at the low end of my healthy weight. I have low to normal blood pressure. Anyway, searching for info on this today, I can't find anyone with such low LDL levels but the term "dangerously low" pops up for women with HDL less than 40.
m still trying to get a clarification. Anyway, the cardiologist put me on Amlodopine and Pravastatin. Now, on a daily basis it seems, my heart rate increases and beats at 90-115 bpm (normally in the mid 70s).
At the same time, I've started on a vegetarian diet to try to lower my cholesterol. To try to make sure I get enough protein, I am using a protein drink (10-14 gr protein each). I drink 1-2 of these per day.
It has dropped my LDL to 39-45 range and blood glucose ranges from 105-111 fasting. A1c 5.1 - 5.3. Prior to the statin I was below 100. I am not overweight, exercise consistently and eat very healthy. So the statin is the culprit. I am wondering if being stricter on carb intake and supplementing with Berberine will help? Or has anyone had better outcomes with other statins like livalo or pravastatin?
t seem overly concerned. He said I could go off the pravastatin and see how my numbers were with diet and exercise alone. I have been on a good routine with proper diet and regular exercise and I am at the low end of my healthy weight. I have low to normal blood pressure. Anyway, searching for info on this today, I can't find anyone with such low LDL levels but the term "dangerously low" pops up for women with HDL less than 40.
FOR ME, it did nothing as it did almost nothing for the cholesterol levels, and in fact some test for liver function was bad and I was taken off the medication and switched to another. Hopefully that does not happen with you. Besides the other statin they switched me to the co-pay was several times the expense of the pravatstatin.
It came back elevated so she took me off of the Pravastatin to see if my enzymes would improve. They did start to level out and she even said that my cholesterol had also dropped down to 150. This made me very happy and I continued to exercise and eat healthy. Recently I went back for a follow up and to have my cholesterol checked again. To my disappointment, my cholesterol went back up to 237 and my LDL is at 158.She seems to think it is genetic.
I am very active in running and watch my diet closely.. However I have to take a low dose of Pravastatin due to the side affects I get for muscle pain. I have notice a strong odor in my urine for awhile now and can not figure out why.. I drink plenty of water..
It has dropped my LDL to 39-45 range and blood glucose ranges from 105-111 fasting. A1c 5.1 - 5.3. Prior to the statin I was below 100. I am not overweight, exercise consistently and eat very healthy. So the statin is the culprit. I am wondering if being stricter on carb intake and supplementing with Berberine will help? Or has anyone had better outcomes with other statins like livalo or pravastatin?
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