Pravastatin and liver damage

Common Questions and Answers about Pravastatin and liver damage

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Avatar m tn potential to increase liver enzymes and cause liver damage, patients must be monitored for normal liver function. At least, that's what the label used to say. Now the FDA has removed this long-standing warning and ruled that patients taking statins no longer need routine monitoring of liver enzymes, but instead can have liver enzymes tested before starting the drugs, and then only as clinically needed.
225237 tn?1333138999 In 4 month-long placebo-controlled trials, 1.7% of Pravastatin-treated patients and 1.2% of placebo-treated patients were discontinued from treatment because of adverse experiences attributed to study drug therapy; this difference was not statistically significant. 6.1 Adverse Clinical Events Short-Term Controlled Trials In the Pravastatin sodium placebo-controlled clinical trials database of 1313 patients (age range 20 to 76 years, 32.4% women, 93.5% Caucasians, 5% Blacks, 0.
179856 tn?1333547362 Moreover, they join others in suggesting that the current labeling for pravastatin and other statins that contraindicates their use in liver disease should be reviewed and amended.
Avatar m tn I take Pravastatin, and my liver Enzymes GGT are high, but ALT and AST are in normal range, not sure why, I have heard different answers some doctors ar concern and others are not
Avatar f tn The study found that the patients on simvastatin achieved the target LDL level of less than 130, more than those on pravastatin (65 percent on simvastatin versus 35 percent on pravastatin). The most common side effects of the statins in general are nausea, gas, and upset stomach. Less common are headache, dizziness, rash, sleep disturbances, muscle pain, cramps, or weakness.
Avatar n tn I was on 40mg of Pravastatin and now am on 80mg. Is my doc just being aggressive? Or is there another reason for the big increase? I welcome any speculations.
Avatar n tn The pravastatin could be the reason, however which of his liver enzymes are elevated? Let us know and I may be able to help you out.
Avatar f tn t seem overly concerned. He said I could go off the pravastatin and see how my numbers were with diet and exercise alone. I have been on a good routine with proper diet and regular exercise and I am at the low end of my healthy weight. I have low to normal blood pressure. Anyway, searching for info on this today, I can't find anyone with such low LDL levels but the term "dangerously low" pops up for women with HDL less than 40.
Avatar f tn //www.drugs.com/sfx/pravastatin-side-effects.html#consumer_Pravastatin Have you discussed this with your doctor? If you take other drugs and/or supplements check with your pharmacist regarding drug interactions.
Avatar m tn FOR ME, it did nothing as it did almost nothing for the cholesterol levels, and in fact some test for liver function was bad and I was taken off the medication and switched to another. Hopefully that does not happen with you. Besides the other statin they switched me to the co-pay was several times the expense of the pravatstatin.
Avatar n tn Two recent trials have compared the clinical outcomes of intensive lipid lowering with atorvastatin 80 mg/day and standard lowering with pravastatin 40 mg/day. In the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT) trial, patients with acute coronary artery syndromes were enrolled, and pravastatin lowered the low-density lipoprotein (LDL)-cholesterol to 2.46 mmol/l, whereas atorvastatin lowered it to 1.60 mmol/l.
Avatar n tn I recently was prescripbed pravastatin and I notice a higher number when I test after a night of fasting in my Blood Glucose. Is there a posibility that could cause the rise.
1806721 tn?1554333407 Welcome and thanks for your question. Statins can cause muscle and joint pain as a side effects. It happens in approx 1 out of every 2,200 users so it's worth mentioning it to your doctor. Keep in mind that muscle and joint pain are the most common medical complaint and a symptom off many conditions so it could very likely not be related to your meds.
553516 tn?1255867219 Patients who take these medications (regularly or daily) should undergo monthly laboratory testing for the first three months of therapy and then every three to six months because of the association between these medications and liver disease.
1806721 tn?1554333407 what is the point of keep taking the products that addressed helping to reduce the cholesterol and gave you all kind of pain, , body aches and woke up every night, and now your doctor suggested you to take statin? does he know that also gives lots of side effect by other users? tell you the truth ! search for yourself and use natural products instead! stay away from all of the above.
Avatar n tn I was prescribed Pravastatin 40mg 15 years ago following a minor heart attack. For at least 5 years I was treated for Goat problems even though I was not having the usual swellings associated with the illness. During the past 3 or 4 years started with Cramp like problems both in my feet, ankles and legs which was getting progressively worse. I mentioned it to various GP's without help until about 3 or 4 months ago when finally one doctor asked "Was I on Statins?
Avatar m tn ) For the past 20 years, I have avoided NSAIDs, acetaminophens, other pain relievers and muscle relaxants because of their adverse effects to liver and kidneys (personally more significant because my dad had kidney disease). Since cannabidiol inhibits the liver's production of cytochrome P450, I am wondering about switching from simvastatin to pravastatin. That would allow me to try CBD, which appears to have minimal side-effects.
Avatar f tn Did they check for impinged nerves? Have you seen a neurologist regarding your chronic headaches? Are they migrainous in nature, muscular or sinus? Did they do a TB test? Statin drugs frequently cause muscle cramps and you should talk to your doctor if this got worse after starting your cholesterol lowering medication, because there can be a serious condition that can develop called rhabdomyolysis.
Avatar m tn 59 yo white male. 1 year post MI with two stents in my RCA. I am active and with high a normal BMI of 25 No problem walking a fast mile or with light exercise. My LVEF was 50% right after MI and 45% 2 months later. due for another echo in 2 months. my lipids are under control - LDL < 70 and TC < 140, with or without the 10 mg pravastatin I am prescribed as I eat mostly a quality plant based diet, low in fats and simple carbs.. My question has to do with drugs.
Avatar f tn I was taken to the ER, where they ruled out heart attack or stroke. They gave me fluids and Zofran and sent me home. Last night, watching TV in bed in an air-conditioned room, it happened again. Consequently, I had trouble sleeping and feel shaky this morning and have a pulsating feeling on the top of my skull. What could this be?
Avatar f tn People can have elavated readings but have little or no damage and you can have normal readings but have damage.
Avatar f tn I have had normal liver enzyme test and a normal ultrasound and ct scan, but I still have extreme bloating. This has been going on for months now. I worry because I binge drank on a nightly basis for about an 8 year span, 3-5(sometimes more) glasses of wine and such. Should I be worried that I have liver damage that is just not showing up? I have changed my diet significantly ( no dairy or gluten) but I am still very bloated. I am sick with worry that I have caused permanent damage.
Avatar f tn The only way to truly ease your mind is by being totally honest with him/her. I have liver damage and kidney damage due to drugs stage 2 liver stage 3 kidney.. if your liver were damaged and you had a flare your belly would be extended/pain upper right you would be lethargic/vomiting.. other symptoms but these being severe.. It is not fun and I would not wish it on anyone.. I contracted hep C from slamming and further continued the damage through pills/alcohol..
Avatar n tn I have never been to hospital, I dont appear to have yellowing of the skin or eyes. What is the likly hood of damage to my liver, and if stoped now could my liver possibly recover from and damege.
1012981 tn?1322603293 My brother has been in the hospital for 12 days for liver damage. His skin and eyes are yellow, abdomen pain and swelling of the stomach. They drained off 12 liters of fluid from stomach area. He's has dementia, no communicating with him that makes any sense. In this situation what is his chance to make it through this? The doctors and nurses are not saying much, but wait and see.