Pravastatin and gemfibrozil

Common Questions and Answers about Pravastatin and gemfibrozil

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Avatar n tn It seems that the main problem was with fenofibrate and pravastatin. The level was pravastatin was greatly increased. But newer info with other statins shows no danger. Atorvastatin serum levels were actually decreased. Jack is very correct that any individual's response can vary a lot from the norm. > Any other natural suggestions on lowering [TG]? I've seen studies that low carb works best, but low Glycemic Index is not that far behind.
Avatar f tn 5 mg/dl and mean LDL cholesterol 111 mg/dl, were randomized to gemfibrozil 1200 mg/d or placebo and were followed up for 5 years. In the VA-HIT study Gemfibrozil resulted in 6 % higher value of HDL cholesterol, 4 % lower for total cholesterol and 31% lower for the triglycerides compared with placebo. There were 134 confirmed strokes, 90%of which were ischemic. 76 occurred in the placebo group and 58 in the gemfibrozil group, for a relative risk reduction of 31%.
501096 tn?1320874932 We have been trying again since May, but I recently discovered that Gemfibrozil (and similar meds) may cause male infertility or reduced fertility. Is this accurate? If so, how long would it take for the medicine to clear his system and his fertility to return? We have 3 healthy kids and have had 2 m/c (2003 & 2008). Thanks for your assistance.
Avatar f tn //www.drugs.com/sfx/pravastatin-side-effects.html#consumer_Pravastatin Have you discussed this with your doctor? If you take other drugs and/or supplements check with your pharmacist regarding drug interactions.
Avatar n tn Two recent trials have compared the clinical outcomes of intensive lipid lowering with atorvastatin 80 mg/day and standard lowering with pravastatin 40 mg/day. In the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT) trial, patients with acute coronary artery syndromes were enrolled, and pravastatin lowered the low-density lipoprotein (LDL)-cholesterol to 2.46 mmol/l, whereas atorvastatin lowered it to 1.60 mmol/l.
7569019 tn?1460135460 now down to 10) 4 days of major charlie horses Dr said stop taking Gemfibrozil.. and to help with the swelling I was put on lasix furosemide 20 mg and pot chloride 20 meg.. I am drinking more water but not peeing anymore than normal..dizzy tho.and sometimes short of breath, especially when walking or talking..how much water should I be drinking, an the muscle cramps and weakness of my legs will they get better? This kills me.. the pain last for hours after a cramp.
Avatar n tn I recently was prescripbed pravastatin and I notice a higher number when I test after a night of fasting in my Blood Glucose. Is there a posibility that could cause the rise.
1806721 tn?1554333407 Welcome and thanks for your question. Statins can cause muscle and joint pain as a side effects. It happens in approx 1 out of every 2,200 users so it's worth mentioning it to your doctor. Keep in mind that muscle and joint pain are the most common medical complaint and a symptom off many conditions so it could very likely not be related to your meds.
Avatar f tn The study found that the patients on simvastatin achieved the target LDL level of less than 130, more than those on pravastatin (65 percent on simvastatin versus 35 percent on pravastatin). The most common side effects of the statins in general are nausea, gas, and upset stomach. Less common are headache, dizziness, rash, sleep disturbances, muscle pain, cramps, or weakness.
Avatar m tn 59 yo white male. 1 year post MI with two stents in my RCA. I am active and with high a normal BMI of 25 No problem walking a fast mile or with light exercise. My LVEF was 50% right after MI and 45% 2 months later. due for another echo in 2 months. my lipids are under control - LDL < 70 and TC < 140, with or without the 10 mg pravastatin I am prescribed as I eat mostly a quality plant based diet, low in fats and simple carbs.. My question has to do with drugs.
1310757 tn?1273645428 Different doctors have just commented on how high it was without telling me answers and I never questioned. With Gemfibrozil it is hovering in the high 200's.
Avatar n tn I was on 40mg of Pravastatin and now am on 80mg. Is my doc just being aggressive? Or is there another reason for the big increase? I welcome any speculations.
600301 tn?1219689156 Exercise, Niacin, Fibrates ( such as gemfibrozil) and some statins can all raise HDL. Alcohol consumption in moderation can also do this. Whereas there is a strong link between low HDL and risk for cardiac death and heart attacks, there is very little evidence that increasing it with drugs ( appart from gemfibrozil and Niacin) actually improves patient's mortality.
Avatar f tn t seem overly concerned. He said I could go off the pravastatin and see how my numbers were with diet and exercise alone. I have been on a good routine with proper diet and regular exercise and I am at the low end of my healthy weight. I have low to normal blood pressure. Anyway, searching for info on this today, I can't find anyone with such low LDL levels but the term "dangerously low" pops up for women with HDL less than 40.
Avatar m tn m still trying to get a clarification. Anyway, the cardiologist put me on Amlodopine and Pravastatin. Now, on a daily basis it seems, my heart rate increases and beats at 90-115 bpm (normally in the mid 70s). At the same time, I've started on a vegetarian diet to try to lower my cholesterol. To try to make sure I get enough protein, I am using a protein drink (10-14 gr protein each). I drink 1-2 of these per day.
Avatar f tn It has dropped my LDL to 39-45 range and blood glucose ranges from 105-111 fasting. A1c 5.1 - 5.3. Prior to the statin I was below 100. I am not overweight, exercise consistently and eat very healthy. So the statin is the culprit. I am wondering if being stricter on carb intake and supplementing with Berberine will help? Or has anyone had better outcomes with other statins like livalo or pravastatin?
225237 tn?1333138999 In 4 month-long placebo-controlled trials, 1.7% of Pravastatin-treated patients and 1.2% of placebo-treated patients were discontinued from treatment because of adverse experiences attributed to study drug therapy; this difference was not statistically significant. 6.1 Adverse Clinical Events Short-Term Controlled Trials In the Pravastatin sodium placebo-controlled clinical trials database of 1313 patients (age range 20 to 76 years, 32.4% women, 93.5% Caucasians, 5% Blacks, 0.
Avatar f tn t seem overly concerned. He said I could go off the pravastatin and see how my numbers were with diet and exercise alone. I have been on a good routine with proper diet and regular exercise and I am at the low end of my healthy weight. I have low to normal blood pressure. Anyway, searching for info on this today, I can't find anyone with such low LDL levels but the term "dangerously low" pops up for women with HDL less than 40.
527657 tn?1214051850 Concurrent use of gemfibrozil and statin drugs such as simvastatin should be avoided. Please discuss the possible risks vs. benefits of taking these 2 drugs with your physician.
Avatar m tn FOR ME, it did nothing as it did almost nothing for the cholesterol levels, and in fact some test for liver function was bad and I was taken off the medication and switched to another. Hopefully that does not happen with you. Besides the other statin they switched me to the co-pay was several times the expense of the pravatstatin.
Avatar n tn s group at Harvard in 1966, it was clearly established that Omega 3 fatty acids and Vitamin C, combined with a low carbohydrate diet, can dramatically reduce your triglyceride levels. Omega 3 fatty acids can help with cholesterol as well.
Avatar f tn It has dropped my LDL to 39-45 range and blood glucose ranges from 105-111 fasting. A1c 5.1 - 5.3. Prior to the statin I was below 100. I am not overweight, exercise consistently and eat very healthy. So the statin is the culprit. I am wondering if being stricter on carb intake and supplementing with Berberine will help? Or has anyone had better outcomes with other statins like livalo or pravastatin?
Avatar n tn My (74 year old) father currently is taking these medications together Pravastatin Sodium 80mg, Zetia 10 mg, Isosorbide Mnonitrate 30 mg, Metoprolol tartrate 50 mg, Plavix 75 mg, Amlodipine Besylate 10 mg, Aspirin (nsaid) 81 mg low dose The doctor told him his liver count is up 66 and the lower range is 64. Would any of these drugs or combination of these drugs make liver count increase?
Avatar n tn Could my heart medicine (metropolol tartrate, gemfibrozil or metformin) be causing me to have a continuing ED problem and would viagra or other med help?? Intercourse is impossible now..Thank you.. This discussion is related to <a href='http://www.medhelp.org/posts/show/493727'>inability to ejaculate</a>.
Avatar n tn I would probably start a statin, and see what happens to your ldl and hdl. If the hdl remains low, then I would add gemfibrozil to raise it ( since Niaspan did not work).
Avatar m tn I take Pravastatin, and my liver Enzymes GGT are high, but ALT and AST are in normal range, not sure why, I have heard different answers some doctors ar concern and others are not
Avatar n tn I'm 55 and have high cholesterol. In early September, I was prescribed a statin for the first time, 40 mg of Pravastatin, to be taken at night. After 2 weeks, I started having muscle pain/weakness in my legs but for the first time in my life had very odd heart palpatations after lying down in bed for about 10 minutes when I was first trying to sleep. I stopped taking the Pravastatin after about 1 month.