Pravachol trial patients
Common Questions and Answers about Pravachol trial patients
pravachol
In the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT) trial, patients with acute coronary artery syndromes were enrolled, and pravastatin lowered the low-density lipoprotein (LDL)-cholesterol to 2.46 mmol/l, whereas atorvastatin lowered it to 1.60 mmol/l. Associated with this, there was a lower rate of clinical events (myocardial infarction, revascularisation) over 2 years with atorvastatin than pravastatin (22.4 versus 26.3%, respectively).
however, I have high blood pressure (norvasc), osteopena (sp) and high cholesteral (pravachol). I really don't want to take fossamax or any more drugs than necessary, but also do not want a recurrence of breast cancer. Is there a clinical study and shows femara vs placebo rather than femara vs tamoifen (novartis trial)? What is the general recommendation? Can you stop femara if side effects become a quality of life issue? Thank you.
does muscle problems from taking the generic pravachol include a burning feeling in the knees which causes pain when walking or bending knees?
My understanding is that the statins with the greatest LDL reducing effect are Crestor, Lipitor, Zocor, and Pravachol, in that order. I don’t mention Leschol and Mevacor since they appear to be rarely used since recently due to the aforementioned being more powerful. Do we have any available solid data on the effects of the various individual statins other than LDL reduction? For example, do we know which ones raise HDL the most? What about effects on particle size or Lp(a), etc.
boc trial is working good for me. I went in with a viral load of 13 million, in 2 weeks i had a viral load of 2 million. 1a . there are others here who have just about cleared. they will chime in.i will let you know next tuesday about results for 6 weeks. thats with n2 weeks of boc added.
Pending results from the Phase 1a trial, Vertex expects to initiate in mid-2008 a Phase 1b trial of VX-500 in HCV patients.
Nothing here that appears to have blockbuster potential as yet…with the potential exception of VX-500, which is their follow-on HCV protease inhibitor drug, currently in pre-human testing. Ideally this would be ready to take over from telaprevir—with better efficacy and milder AEs—around 2013 or so.
http://caps.fool.com/Ticker/VRTX.
I was on medication in and out as I develop side effects to the statin drugs. I was on Lipitor, then on Pravachol and lastly on Crestor. None of them had problems loweting the Choesterol levels, but muscle and joint pain even with Vit D and Co Q10 as prescribed my physician. However, I came off crestor yesterday as I started feeling Dizzy. I am normally a "healthy", active energetic person. Now my doc thinks we should try Zetia which is in a different family of drugs.
Lipitor (atorvastatin), Lescol (fluvastatin), Mevacor (lovastatin), Altoprev (lovastatin extended-release), Livalo (pitavastatin), Pravachol (pravastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Combination products include: Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).
The new labels will warn patients about:
Memory loss and mental confusion.
never came back), resurgence of the peripheral neuropathy which I first got years ago from a year on Pravachol (statin) all the way up to my knees, worsening of my lung disease (which I discovered started with the Pravachol, stopped when I was off statins, and grew again when I went back on) AND wildly erratic heartbeats and tachycardia (all the way up to 140 beats per minute).
Most trial exclude post-transplant patients. The only trial that would be conducted would be through transplant centers
Have you spoken to your transplant center? They would know about any clinical trials that they will be conducting that you would qualify for.
You will need to be under the care of a transplant center if you should make any changes to the drugs you are taking.
No other symptoms what so ever. Find it hard to loose weight even I try, take toprol and pravachol, was on Z-pack for strep throat when CT was done. Someone?
Our investigational interferon-free regimen has shown particular promise in treating patients with HCV genotype-1b so we have decided to enroll these patients in our Phase 3 trial program. Our goal is for an interferon-free future and ensuring patients are treated with the most effective treatment for them individually.
Data generated from this Phase 3 trial in treatment-failure patients, as well as data from the ongoing Phase 3 ADVANCE trial in treatment-naive patients, may further contribute to the emerging profile of telaprevir to address the significant medical need in both treatment-naive and treatment-failure patients.
My psychiatrist has me on Lamictal, Effexor, Neurontin, Wellbutrin, and Nuvigil. From my PCP I take Pravachol and Lisinopril. Is it safe to take all these together? All answers are appreciated.
My blood preasure has been high since before I found out I was a diabetic. He also has me on pravachol. My cholestrol was high before I was told I was a diabetic. It has read the same since I have been on this drug. Would it be wiser to change either of the drugs or to add plavix? I have been on pravachol for at least 6 years and diabetic only two.
Another area I have noticed in your forum, is the effect of caffine on blood sugars.
Its been a couple years since I have been here. I did a trial in 2013 with someone that was dosing based on tsh and I eventually gave up. Now looking back I have discovered that I probably was not absorbing the medication. I also know that supplementing with iodine likely sabotaged any progress I was making since is causes tsh to rise in addition to tanking my iron. These are my observations based on the last two years of monthly labwork.
In the clinical trial design about obesity with type 2 diabetes , the exclusion criteria includes patients should be excluded if they have fasting glucose levels greater than 270 mg/dl, I wonder the the clinical significance of the 270 mg/dl? In the T2DM clinical guidance, I didn't find this value.
I take prevacid for heartburn and pravachol for high cholesterol; also using mupirocin ointment since I had sinus surgery in September.
No, they took patients that were on nucs and then added the vaccine shots for 24 weeks on half of them, continuIng nucs, then stopping all treatment for both groups and observing the resurgence of hbv dna. The hope was that the vaccine shots will keep the hbv dna suppressed in a large or significantly larger percentage of the vaccine add on group at the 24 week mark after EOT. Now they see that this endpoint will not be met.
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